Journal
JOURNAL OF BIOPHOTONICS
Volume 12, Issue 7, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jbio.201900019
Keywords
Fresnel reflection; refractive index; single fiber reflectance; transparent; turbid
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Funding
- NWO-TTW [12702]
- Netherlands Organization for Scientific Research [12702]
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A method using single fiber reflectance spectroscopy to measure the refractive indices of transparent and turbid media over a broad wavelength range is presented and tested. For transparent liquid samples, the accuracy is within 0.2%, and the accuracy increases with increasing wavelength. For liquid turbid media, the accuracy is within 0.3% and increases with decreasing wavelength. For solid turbid samples, such as human skin, the accuracy critically depends on the optical contact between the fiber and sample surface. It is demonstrated that this technique has the potential to measure refractive indices of biological tissue in vivo.
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