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Myoungsun Son et al.
BLOOD (2016)
Partial sleep deprivation activates the DNA damage response (DDR) and the senescence-associated secretory phenotype (SASP) in aged adult humans
Judith E. Carroll et al.
BRAIN BEHAVIOR AND IMMUNITY (2016)
Role of Melatonin in the Regulation of Differentiation of T Cells Producing Interleukin-17 (Th17)
E. M. Kuklina et al.
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2016)
MicroRNA-125b regulates microglia activation and motor neuron death in ALS
C. Parisi et al.
CELL DEATH AND DIFFERENTIATION (2016)
Melatonin and Synthetic Melatoninergic Agonists in Psychiatric and Age-associated Disorders: Successful and Unsuccessful Approaches
Ruediger Hardeland
CURRENT PHARMACEUTICAL DESIGN (2016)
C66 ameliorates diabetic nephropathy in mice by both upregulating NRF2 function via increase in miR-200a and inhibiting miR-21
Hao Wu et al.
DIABETOLOGIA (2016)
Emerging role of long noncoding RNAs as regulators of innate immune cell development and inflammatory gene expression
Roland Elling et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2016)
MiR-150 impairs inflammatory cytokine production by targeting ARRB-2 after blocking CD28/B7 costimulatory pathway
Wei Sang et al.
IMMUNOLOGY LETTERS (2016)
Nicotinic acid inhibits NLRP3 inflammasome activation via SIRT1 in vascular endothelial cells
Yanxiang Li et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2016)
Overexpression of miR-200a protects cardiomyocytes against hypoxia-induced apoptosis by modulating the kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 signaling axis
Xiaoxia Sun et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2016)
The TORC1-activated Proteins, p70S6K and GRB10, Regulate IL-4 Signaling and M2 Macrophage Polarization by Modulating Phosphorylation of Insulin Receptor Substrate-2
Kristi J. Warren et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
MicroRNA-125b Prevents Cardiac Dysfunction in Polymicrobial Sepsis by Targeting TRAF6-Mediated Nuclear Factor κB Activation and p53-Mediated Apoptotic Signaling
He Ma et al.
JOURNAL OF INFECTIOUS DISEASES (2016)
Long noncoding RNAs as regulators of Toll-like receptor signaling and innate immunity
Michael B. Murphy et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2016)
Sirt1 decreased adipose inflammation by interacting with Akt2 and inhibiting mTOR/S6K1 pathway in mice
Zhenjiang Liu et al.
JOURNAL OF LIPID RESEARCH (2016)
miR-124a and miR-155 enhance differentiation of regulatory T cells in patients with neuropathic pain
Jens Heyn et al.
JOURNAL OF NEUROINFLAMMATION (2016)
Melatonin modulates neonatal brain inflammation through endoplasmic reticulum stress, autophagy, and miR-34a/silent information regulator 1 pathway
Silvia Carloni et al.
JOURNAL OF PINEAL RESEARCH (2016)
Long noncoding RNA H19 mediates melatonin inhibition of premature senescence of c-kit+ cardiac progenitor cells by promoting miR-675
Benzhi Cai et al.
JOURNAL OF PINEAL RESEARCH (2016)
MicroRNA-9 regulates the development of knee osteoarthritis through the NF-kappaB1 pathway in chondrocytes
Ronghe Gu et al.
MEDICINE (2016)
Melatonin enhances arsenic trioxide-induced cell death via sustained upregulation of Redd1 expression in breast cancer cells
Sun-Mi Yun et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2016)
miR-20a induces cisplatin resistance of a human gastric cancer cell line via targeting CYLD
Mingxia Zhu et al.
MOLECULAR MEDICINE REPORTS (2016)
Melatonin administration reverses the alteration of amyloid precursor protein-cleaving secretases expression in aged mouse hippocampus
Sujira Mukda et al.
NEUROSCIENCE LETTERS (2016)
Role of miR-155 in fluorooctane sulfonate-induced oxidative hepatic damage via the Nrf2-dependent pathway
Chong Wan et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2016)
microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB
Keith M. Giles et al.
ONCOTARGET (2016)
Melatonin protects skin keratinocyte from hydrogen peroxide-mediated cell death via the SIRT1 pathway
Ju-Hee Lee et al.
ONCOTARGET (2016)
Multitargeting activity of miR-24 inhibits long-term melatonin anticancer effects
Federica Mori et al.
ONCOTARGET (2016)
Protective effect of melatonin on soluble Aβ1-42-induced memory impairment, astrogliosis, and synaptic dysfunction via the Musashi1/Notch1/Hes1 signaling pathway in the rat hippocampus
Shuman Zhang et al.
ALZHEIMERS RESEARCH & THERAPY (2016)
Altered microRNA-9 Expression Level is Directly Correlated with Pathogenesis of Nonalcoholic Fatty Liver Disease by Targeting Onecut2 and SIRT1
Ran Ao et al.
MEDICAL SCIENCE MONITOR (2016)
Human Leukemic Cells performing Oxidative Phosphorylation (OXPHOS) Generate an Antioxidant Response Independently of Reactive Oxygen species (ROS) Production
Abrar Ul Haq Khan et al.
EBIOMEDICINE (2016)
Modulation of Macrophage Polarization and HMGB1-TLR2/TLR4 Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice
Vengadeshprabhu Karuppagounder et al.
PLOS ONE (2016)
被撤回的出版物: HMGB1 Facilitated Macrophage Reprogramming towards a Proinflammatory M1-like Phenotype in Experimental Autoimmune Myocarditis Development (Retracted article. See vol. 12, 2022)
Zhaoliang Su et al.
SCIENTIFIC REPORTS (2016)
Melatonin prevents acute kidney injury in severely burned rats via the activation of SIRT1
Xiao-Zhi Bai et al.
SCIENTIFIC REPORTS (2016)
The role of miR-146a on NF-κB expression level in human umbilical vein endothelial cells under hyperglycemic condition
K. Kamali et al.
BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY (2016)
MicroRNA signature of inflamed lymphatic endothelium and role of miR-9 in lymphangiogenesis and inflammation
Sanjukta Chakraborty et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2015)
BRAF activated non-coding RNA (BANCR) promoting gastric cancer cells proliferation via regulation of NF-κB1
Zhi-Xin Zhang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Melatonin ameliorates ER stress-mediated hepatic steatosis through miR-23a in the liver
Seung-Jae Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Sirtuin regulation in aging and injury
Ninu Poulose et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)
Reciprocal inhibition between miR-26a and NF-κB regulates obesity-related chronic inflammation in chondrocytes
Qingyun Xie et al.
BIOSCIENCE REPORTS (2015)
Methylseleninic acid activates Keap1/Nrf2 pathway via up-regulating miR-200a in human oesophageal squamous cell carcinoma cells
Mei Liu et al.
BIOSCIENCE REPORTS (2015)
Melatonin attenuates the TLR4-mediated inflammatory response through MyD88-and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer
Luiz Gustavo A. Chuffa et al.
BMC CANCER (2015)
MicroRNA let-7 Modulates the Immune Response to Mycobacterium tuberculosis Infection via Control of A20, an Inhibitor of the NF-κB Pathway
Manish Kumar et al.
CELL HOST & MICROBE (2015)
Role of growth hormone in maturation and activation of dendritic cells via miR-200a and the Keap1/Nrf2 pathway
Qiu-Liang Liu et al.
CELL PROLIFERATION (2015)
Sirtuin-dependent clock control: new advances in metabolism, aging and cancer
Selma Masri
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2015)
Upregulation of microRNA-126 in Hepatic Stellate Cells May Affect Pathogenesis of Liver Fibrosis Through the NF-κB Pathway
Xiao Feng et al.
DNA AND CELL BIOLOGY (2015)
Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice
Jose A. Garcia et al.
FASEB JOURNAL (2015)
MicroRNA-7 activates Nrf2 pathway by targeting Keap1 expression
Sayan Kabaria et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Age-related loss of hepatic Nrf2 protein homeostasis: Potential role for heightened expression of miR-146a
Eric J. Smith et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Lack of IL-17 signaling decreases liver fibrosis in murine schistosomiasis japonica
Yuxia Zhang et al.
INTERNATIONAL IMMUNOLOGY (2015)
MicroRNA-7/NF-κB signaling regulatory feedback circuit regulates gastric carcinogenesis
Xiao-Di Zhao et al.
JOURNAL OF CELL BIOLOGY (2015)
The miR-30a Negatively Regulates IL-17-Mediated Signal Transduction by Targeting Traf3ip2
Qun Wan et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2015)
Membrane receptor-dependent Notch1/Hes1 activation by melatonin protects against myocardial ischemia-reperfusion injury: invivo and invitro studies
Liming Yu et al.
JOURNAL OF PINEAL RESEARCH (2015)
Reduced silent information regulator 1 signaling exacerbates myocardial ischemia-reperfusion injury in type 2 diabetic rats and the protective effect of melatonin
Liming Yu et al.
JOURNAL OF PINEAL RESEARCH (2015)
Melatonin reverses H2O2-induced premature senescence in mesenchymal stem cells via the SIRT1-dependent pathway
Long Zhou et al.
JOURNAL OF PINEAL RESEARCH (2015)
Melatonin alleviates brain injury in mice subjected to cecal ligation and puncture via attenuating inflammation, apoptosis, and oxidative stress: the role of SIRT1 signaling
Lei Zhao et al.
JOURNAL OF PINEAL RESEARCH (2015)
Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells
Jiraporn Panmanee et al.
JOURNAL OF PINEAL RESEARCH (2015)
High glucose induces renal tubular epithelial injury via Sirt1/NF-kappaB/microR-29/Keap1 signal pathway
Ling Zhou et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
High-mobility group box 1 is a novel deacetylation target of Sirtuin1
May M. Rabadi et al.
KIDNEY INTERNATIONAL (2015)
Interplay between Intravitreal RvD1 and Local Endogenous Sirtuin-1 in the Protection from Endotoxin-Induced Uveitis in Rats
S. Rossi et al.
MEDIATORS OF INFLAMMATION (2015)
Melatonin Protects Methamphetamine-Induced Neuroinflammation Through NF-κB and Nrf2 Pathways in Glioma Cell Line
Pichaya Jumnongprakhon et al.
NEUROCHEMICAL RESEARCH (2015)
Melatonin and brain inflammaging
Ruediger Hardeland et al.
PROGRESS IN NEUROBIOLOGY (2015)
Loss of tumor suppressive microRNA-31 enhances TRADD/NF-κB signaling in glioblastoma
Rajani Rajbhandari et al.
ONCOTARGET (2015)
MicroRNA-212 negatively regulates starvation induced autophagy in prostate cancer cells by inhibiting SIRT1 and is a modulator of angiogenesis and cellular senescence
Malathi Ramalinga et al.
ONCOTARGET (2015)
MiR-210 inhibits NF-κB signaling pathway by targeting DR6 in osteoarthritis
Dawei Zhang et al.
SCIENTIFIC REPORTS (2015)
Inhibition of miR-29 has a significant lipid-lowering benefit through suppression of lipogenic programs in liver
C. Lisa Kurtz et al.
SCIENTIFIC REPORTS (2015)
Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment
Rebecca B. Weinberg et al.
FRONTIERS IN NEUROSCIENCE (2015)
Modulation of tumorigenesis by the pro-inflammatory microRNA miR-301a in mouse models of lung cancer and colorectal cancer
Xiaodong Ma et al.
CELL DISCOVERY (2015)
Unacylated Ghrelin Induces Oxidative Stress Resistance in a Glucose Intolerance and Peripheral Artery Disease Mouse Model by Restoring Endothelial Cell miR-126 Expression
Gabriele Togliatto et al.
DIABETES (2015)
Melatonin stimulates the nonamyloidogenic processing of βAPP through the positive transcriptional regulation of ADAM10 and ADAM17
Mayuri Shukla et al.
JOURNAL OF PINEAL RESEARCH (2015)
Melatonin prevents cell death and mitochondrial dysfunction via a SIRT1-dependent mechanism during ischemic-stroke in mice
Yang Yang et al.
JOURNAL OF PINEAL RESEARCH (2015)
Let-7 miRNAs Modulate the Activation of NF-κB by Targeting TNFAIP3 and Are Involved in the Pathogenesis of Lupus Nephritis
Jun Liu et al.
PLOS ONE (2015)
Deacetylation-mediated interaction of SIRT1-HMGB1 improves survival in a mouse model of endotoxemia
Jung Seok Hwang et al.
SCIENTIFIC REPORTS (2015)
miR-340 Reverses Cisplatin Resistance of Hepatocellular Carcinoma Cell Lines by Targeting Nrf2-dependent Antioxidant Pathway
Liang Shi et al.
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION (2014)
Melatonin and oestrogen treatments were able to improve neuroinflammation and apoptotic processes in dentate gyrus of old ovariectomized female rats
Roman A. Kireev et al.
AGE (2014)
Rare Individual Amyloid-β Oligomers Act on Astrocytes to Initiate Neuronal Damage
Priyanka Narayan et al.
BIOCHEMISTRY (2014)
MicroRNA-125b protects against myocardial ischaemia/reperfusion injury via targeting p53-mediated apoptotic signalling and TRAF6
Xiaohui Wang et al.
CARDIOVASCULAR RESEARCH (2014)
Vascular importance of themiR-212/132 cluster
Regalla Kumarswamy et al.
EUROPEAN HEART JOURNAL (2014)
RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy- and 20,23-dihydroxyvitamin D
Andrzej T. Slominski et al.
FASEB JOURNAL (2014)
Aldose reductase regulates miR-200a-3p/141-3p to coordinate Keap1-Nrf2, Tgfβ1/2, and Zeb1/2 signaling in renal mesangial cells and the renal cortex of diabetic mice
Jie Wei et al.
FREE RADICAL BIOLOGY AND MEDICINE (2014)
Cryptosporidium parvum induces SIRT1 expression in host epithelial cells through downregulating let-7i
Hongguan Xie et al.
HUMAN IMMUNOLOGY (2014)
Melatonin, Noncoding RNAs, Messenger RNA Stability and Epigenetics-Evidence, Hints, Gaps and Perspectives
Ruediger Hardeland
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)
Upregulation of miR-181 Decreases c-Fos and SIRT-1 in the Hippocampus of 3xTg-AD Mice
Carlos J. Rodriguez-Ortiz et al.
JOURNAL OF ALZHEIMERS DISEASE (2014)
Fasting protects liver from ischemic injury through Sirt1-mediated downregulation of circulating HMGB1 in mice
Andreas Rickenbacher et al.
JOURNAL OF HEPATOLOGY (2014)
MicroRNA-7 Protects against 1-Methyl-4-Phenylpyridinium-Induced Cell Death by Targeting RelA
Doo Chul Choi et al.
JOURNAL OF NEUROSCIENCE (2014)
Melatonin receptor-mediated protection against myocardial ischemia/reperfusion injury: role of SIRT1
Liming Yu et al.
JOURNAL OF PINEAL RESEARCH (2014)
Constructing and characterizing a bioactive small molecule and microRNA association network for Alzheimer's disease
Fanlin Meng et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2014)
Neuronal driven pre-plaque inflammation in a transgenic rat model of Alzheimer's disease
Cecilia E. Hanzel et al.
NEUROBIOLOGY OF AGING (2014)
Melatonin reduced microglial activation and alleviated neuroinflammation induced neuron degeneration in experimental traumatic brain injury: Possible involvement of mTOR pathway
Ke Ding et al.
NEUROCHEMISTRY INTERNATIONAL (2014)
Long-Term Effects of Peripubertal Binge EtOH Exposure on Hippocampal microRNA Expression in the Rat
Sarah A. Prins et al.
PLOS ONE (2014)
Traumatic Brain Injury Dysregulates MicroRNAs to Modulate Cell Signaling in Rat Hippocampus
Liang Liu et al.
PLOS ONE (2014)
Interleukin-17 in human inflammatory diseases
Arezoo Gowhari Shabgah et al.
POSTEPY DERMATOLOGII I ALERGOLOGII (2014)
NOVEL ROLE OF RESVERATROL: SUPPRESSION OF HIGH-MOBILITY GROUP PROTEIN BOX 1 NUCLEOCYTOPLASMIC TRANSLOCATION BY THE UPREGULATION OF SIRTUIN 1 IN SEPSIS-INDUCED LIVER INJURY
Wei Xu et al.
SHOCK (2014)
Melatonin Improves Mitochondrial Function by Promoting MT1/SIRT1/PGC-1 Alpha-Dependent Mitochondrial Biogenesis in Cadmium-Induced Hepatotoxicity In Vitro
Pan Guo et al.
TOXICOLOGICAL SCIENCES (2014)
Long non-coding RNAs in the regulation of the immune response
James A. Heward et al.
TRENDS IN IMMUNOLOGY (2014)
Ligand-activated peroxisome proliferator-activated receptor-δ and -γ inhibit lipopolysaccharide-primed release of high mobility group box 1 through upregulation of SIRT1
J. S. Hwang et al.
CELL DEATH & DISEASE (2014)
miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas
S. Haemmig et al.
CELL DEATH & DISEASE (2014)
MiR-9 promotes microglial activation by targeting MCPIP1
Honghong Yao et al.
NATURE COMMUNICATIONS (2014)
A novel crosstalk between BRCA1 and sirtuin 1 in ovarian cancer
Da Li et al.
SCIENTIFIC REPORTS (2014)
Correlated Inflammatory Responses and Neurodegeneration in Peptide-Injected Animal Models of Alzheimer's Disease
James G. McLarnon
BIOMED RESEARCH INTERNATIONAL (2014)
Regulation of TIMP3 in diabetic nephropathy: a role for microRNAs
Loredana Fiorentino et al.
ACTA DIABETOLOGICA (2013)
Aging and vascular dysfunction: beneficial melatonin effects
Luigi Fabrizio Rodella et al.
AGE (2013)
Antidicer RNAse activity of monocyte chemotactic protein-induced protein-1 is critical for inducing angiogenesis
Arpita Roy et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2013)
Treatment implications of the altered cytokine-insulin axis in neurodegenerative disease
Ian A. Clark et al.
BIOCHEMICAL PHARMACOLOGY (2013)
SIRT1 Mediates Central Circadian Control in the SCN by a Mechanism that Decays with Aging
Hung-Chun Chang et al.
CELL (2013)
MicroRNA-182 Promotes Tumor Cell Growth by Targeting Transcription Elongation Factor A-like 7 in Endometrial Carcinoma
Ying Guo et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2013)
MicroRNA-Mediated Epigenetic Silencing of Sirtuin1 Contributes to Impaired Angiogenic Responses
Ingo Volkmann et al.
CIRCULATION RESEARCH (2013)
Down-regulation of NAMPT expression by miR-182 is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation
Xin-Yu Chen et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2013)
Melatonin in Alzheimer's Disease
Li Lin et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Melatonin: Buffering the Immune System
Antonio Carrillo-Vico et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
JAK2/STAT3 activation by melatonin attenuates the mitochondrial oxidative damage induced by myocardial ischemia/reperfusion injury
Yang Yang et al.
JOURNAL OF PINEAL RESEARCH (2013)
Melatonin and the theories of aging: a critical appraisal of melatonin's role in antiaging mechanisms
Ruediger Hardeland
JOURNAL OF PINEAL RESEARCH (2013)
Epigenetic inactivation of miR-9 family microRNAs in chronic lymphocytic leukemia - implications on constitutive activation of NFκB pathway
Lu Qian Wang et al.
MOLECULAR CANCER (2013)
Histone Deacetylase Inhibition Overcomes Drug Resistance through a miRNA-Dependent Mechanism
Tracy Murray-Stewart et al.
MOLECULAR CANCER THERAPEUTICS (2013)
Natural RNA circles function as efficient microRNA sponges
Thomas B. Hansen et al.
NATURE (2013)
Circular RNAs are a large class of animal RNAs with regulatory potency
Sebastian Memczak et al.
NATURE (2013)
Neuroprotective Function of DJ-1 in Parkinson's Disease
Hiroyoshi Ariga et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
MiR-125b Reduces Porcine Reproductive and Respiratory Syndrome Virus Replication by Negatively Regulating the NF-κB Pathway
Dang Wang et al.
PLOS ONE (2013)
Sleep Facilitates Clearance of Metabolites from the Brain: Glymphatic Function in Aging and Neurodegenerative Diseases
Andrew R. Mendelsohn et al.
REJUVENATION RESEARCH (2013)
miR-128 exerts pro-apoptotic effect in a p53 transcription-dependent and -independent manner via PUMA-Bak axis
Y. K. Adlakha et al.
CELL DEATH & DISEASE (2013)
MicroRNA-34a regulates the longevity-associated protein SIRT I in coronary artery disease: effect of statins on SIRT I and microRNA-34a expression
Tsuyoshi Tabuchi et al.
CLINICAL SCIENCE (2012)
miR-301a Is a Candidate Oncogene that Targets the Homeobox Gene Gax in Human Hepatocellular Carcinoma
Peng Zhou et al.
DIGESTIVE DISEASES AND SCIENCES (2012)
microRNA-210 negatively regulates LPS-induced production of proinflammatory cytokines by targeting NF-κB1 in murine macrophages
Jianni Qi et al.
FEBS LETTERS (2012)
Gene regulation by melatonin linked to epigenetic phenomena
Ahmet Korkmaz et al.
GENE (2012)
Mitochondrial DNA and inflammatory diseases
Germaine Escames et al.
HUMAN GENETICS (2012)
Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
Kenichi Shimada et al.
IMMUNITY (2012)
Looking in the miR-ror: TGF-β-mediated activation of NF-κB in glioma
Christine E. Eyler et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
TGF-β induces miR-182 to sustain NF-κB activation in glioma subsets
Libing Song et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Target Gene Repression Mediated by miRNAs miR-181c and miR-9 Both of Which Are Down-regulated by Amyloid-β
Nicole Schonrock et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2012)
Neurons from senescence-accelerated SAMP8 mice are protected against frailty by the sirtuin 1 promoting agents melatonin and resveratrol
Rosa Cristofol et al.
JOURNAL OF PINEAL RESEARCH (2012)
Alzheimer's disease: pathological mechanisms and the beneficial role of melatonin
Sergio A. Rosales-Corral et al.
JOURNAL OF PINEAL RESEARCH (2012)
Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling
Ruediger Hardeland et al.
JOURNAL OF PINEAL RESEARCH (2012)
Interleukin-6 autocrine signaling mediates melatonin MT1/2 receptor-induced STAT3 Tyr705 phosphorylation
Winnie W. I. Lau et al.
JOURNAL OF PINEAL RESEARCH (2012)
Melatonin modulates TLR4-mediated inflammatory genes through MyD88-and TRIF-dependent signaling pathways in lipopolysaccharide-stimulated RAW264.7 cells
Mi-Zhen Xia et al.
JOURNAL OF PINEAL RESEARCH (2012)
Melatonin suppresses proinflammatory mediators in lipopolysaccharide-stimulated CRL1999 cells via targeting MAPK, NF-?B, c/EBPß, and p300 signaling
Dingbo Shi et al.
JOURNAL OF PINEAL RESEARCH (2012)
Up-Regulation of microRNA-126 May Contribute to Pathogenesis of Ulcerative Colitis via Regulating NF-kappaB Inhibitor IκBα
Xiao Feng et al.
PLOS ONE (2012)
MicroRNAs miR-125a and miR-125b constitutively activate the NF-κB pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20)
Sang-Woo Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β
Jeffrey J. Iliff et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Aging and Immune Function: Molecular Mechanisms to Interventions
Subramaniam Ponnappan et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
miR-301a as an NF-κB activator in pancreatic cancer cells
Zhongxin Lu et al.
EMBO JOURNAL (2011)
Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype
Antero Salminen et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2011)
Suppressor of cytokine signaling 1 (SOCS1) limits NFκB signaling by decreasing p65 stability within the cell nucleus
Julia Strebovsky et al.
FASEB JOURNAL (2011)
Sirt1 and mir-9 expression is regulated during glucose-stimulated insulin secretion in pancreatic β-islets
Deepti Ramachandran et al.
FEBS JOURNAL (2011)
miR-200a Regulates SIRT1 Expression and Epithelial to Mesenchymal Transition (EMT)-like Transformation in Mammary Epithelial Cells
Gabriel Eades et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
miR-200a Regulates Nrf2 Activation by Targeting Keap1 mRNA in Breast Cancer Cells
Gabriel Eades et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: effects on NF-κB and Nrf2 cascades
Geeta Negi et al.
JOURNAL OF PINEAL RESEARCH (2011)
MicroRNA and gene expression analysis of melatonin-exposed human breast cancer cell lines indicating involvement of the anticancer effect
Seung Eun Lee et al.
JOURNAL OF PINEAL RESEARCH (2011)
Melatonin protects liver against ischemia and reperfusion injury through inhibition of toll-like receptor signaling pathway
Jung-Woo Kang et al.
JOURNAL OF PINEAL RESEARCH (2011)
miR-27b*, an oxidative stress-responsive microRNA modulates nuclear factor-kB pathway in RAW 264.7 cells
Sivasubramani Thulasingam et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2011)
Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase
Virginia Guarani et al.
NATURE (2011)
Melatonin-A pleiotropic, orchestrating regulator molecule
Ruediger Hardeland et al.
PROGRESS IN NEUROBIOLOGY (2011)
Parkinson's Disease as a Neuroendocrine Disorder of Circadian Function: Dopamine-Melatonin Imbalance and the Visual System in the Genesis and Progression of the Degenerative Process
Gregory L. Willis
REVIEWS IN THE NEUROSCIENCES (2011)
Therapeutic potential of melatonin and its analogs in Parkinson’s disease: focus on sleep and neuroprotection
Venkatramanujam Srinivasan et al.
Therapeutic Advances in Neurological Disorders (2011)
miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues
Laura R. Saunders et al.
AGING-US (2010)
The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
Jean -Philippe Coppe et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)
Inflammation, genetic background and longevity
Giuseppina Candore et al.
BIOGERONTOLOGY (2010)
miR-126 Is Downregulated in Cystic Fibrosis Airway Epithelial Cells and Regulates TOM1 Expression
Irene K. Oglesby et al.
JOURNAL OF IMMUNOLOGY (2010)
SASP reflects senescence
Andrew R. J. Young et al.
EMBO REPORTS (2009)
Differential Roles of Interleukin-17A and-17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses
Harumichi Ishigame et al.
IMMUNITY (2009)
Anti-aging properties of melatonin in an in vitro murine senescence model: involvement of the sirtuin 1 pathway
M. Tajes et al.
JOURNAL OF PINEAL RESEARCH (2009)
Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease
James M. Olcese et al.
JOURNAL OF PINEAL RESEARCH (2009)
Neuroprotection by Radical Avoidance: Search for Suitable Agents
Ruediger Hardeland
MOLECULES (2009)
SASPense and DDRama in cancer and ageing
Marzia Fumagalli et al.
NATURE CELL BIOLOGY (2009)
Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1
Yasukazu Nakahata et al.
SCIENCE (2009)
The tumor-promoting activity of 2-acetylaminofluorene is associated with disruption of the p53 signaling pathway and the balance between apoptosis and cell proliferation
Igor R. Pogribny et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2009)
Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice
Kathryn Moynihan Ramsey et al.
AGING CELL (2008)
Melatonin treatment does not improve rheumatoid arthritis
Georges J. Maestroni et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2008)
Evaluation of potential pro-survival pathways regulated by melatonin in a murine senescence model
Javier Gutierrez-Cuesta et al.
JOURNAL OF PINEAL RESEARCH (2008)
Melatonin decreases TLR3-mediated inflammatory factor expression via inhibition of NF-κB activation in respiratory syncytial virus-infected RAW264.7 macrophages
Sheng-Hai Huang et al.
JOURNAL OF PINEAL RESEARCH (2008)
Melatonin and the Immune System in Aging
Daniel P. Cardinali et al.
NEUROIMMUNOMODULATION (2008)
Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
Jean-Philippe Coppe et al.
PLOS BIOLOGY (2008)
Nutrient sensing and inflammation in metabolic diseases
Goekhan S. Hotamisligil et al.
NATURE REVIEWS IMMUNOLOGY (2008)
No Immune Risk Profile among individuals who reach 100 years of age:: Findings from the Swedish NONA immune longitudinal study
Jan Strindhall et al.
EXPERIMENTAL GERONTOLOGY (2007)
The function of interleukin 17 in the pathogenesis of rheumatoid arthritis
Agnieszka Paradowska et al.
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS (2007)
Immunological biomarkers of ageing in man: changes in both innate and adaptive immunity are associated with health and longevity
Olga DelaRosa et al.
BIOGERONTOLOGY (2006)
Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding
Wu-Guo Deng et al.
BLOOD (2006)
Melatonin - Nature's most versatile biological signal?
S. R. Pandi-Perumal et al.
FEBS JOURNAL (2006)
The role of melatonin in immuno-enhancement: potential application in cancer
SC Miller et al.
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2006)
The role of ML-23 and other melatonin analogues in the treatment and management of Parkinson's disease
GL Willis
DRUG NEWS & PERSPECTIVES (2005)
The melatonin-cytokine connection in rheumatoid arthritis
M Cutolo et al.
ANNALS OF THE RHEUMATIC DISEASES (2005)
A review of the multiple actions of melatonin on the immune system
A Carrillo-Vico et al.
ENDOCRINE (2005)
Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg2576 mice:: Implications for clinical trials
J Quinn et al.
BRAIN RESEARCH (2005)
Human lymphocyte-synthesized melatonin is involved in the regulation of the interleukin-2/interleukin-2 receptor system
A Carrillo-Vico et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
Does melatonin play a disease-promoting role in rheumatoid arthritis?
GJM Maestroni et al.
JOURNAL OF NEUROIMMUNOLOGY (2005)
The mammalian circadian timing system: from gene expression to physiology
F Gachon et al.
CHROMOSOMA (2004)
Evidence of melatonin synthesis by human lymphocytes and its physiological significance: possible role as intracrine, autocrine, and/or paracrine substance
A Carrillo-Vico et al.
FASEB JOURNAL (2004)
Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease
E Matsubara et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Melatonin counteracts the inhibitory effect of PGE2 on IL-2 production in human lymphocytes via its mt1 membrane receptor
A Carrillo-Vico et al.
FASEB JOURNAL (2003)
Regulation of NF-kappa B signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA
A Ryo et al.
MOLECULAR CELL (2003)
Effects of aging on central and peripheral mammalian clocks
S Yamazaki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Modulation of bronchial epithelial cells by IL-17
M Kawaguchi et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2001)
IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines
S Molet et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2001)
Pineal indoles stimulate the gene expression of immunomodulating cytokines
F Liu et al.
JOURNAL OF NEURAL TRANSMISSION (2001)
An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease
MA Pappolla et al.
JOURNAL OF NEURAL TRANSMISSION (2000)