Journal
INTERNATIONAL JOURNAL OF EATING DISORDERS
Volume 52, Issue 5, Pages 591-596Publisher
WILEY
DOI: 10.1002/eat.23048
Keywords
anorexia nervosa; atypical anorexia nervosa; body composition; bone density; bone health; dual-energy x-ray absorptiometry; DXA; eating disorders; obesity; overweight
Funding
- American Pediatric Society
- Eunice Kennedy Shriver National Institute of Child Health and Human Development [5R01HD08216602, K12 HD000850]
- National Institute of Diabetes and Digestive and Kidney Diseases [K23DK100558]
- National Institute of Mental Health [K23 MH115184]
- Hilda and Preston Davis Foundation
- American Academy of Pediatrics
- Pediatric Scientist Development Program [K12 HD000850]
- National Institutes of Health [5R01HD08216602, K23DK100558, K23 MH115184]
Ask authors/readers for more resources
Objective To compare bone mineral density (BMD) and body composition among adolescents: (a) with atypical anorexia nervosa (AAN) versus anorexia nervosa (AN) and (b) those with and without a prior history of overweight. Method Electronic medical records of patients 9-20 years with AN or AAN who underwent dual-energy x-ray absorptiometry scans were retrospectively reviewed and analyzed. Results A total of 286 adolescents with AN or AAN were included. In linear regression models, AAN was associated with greater Z-scores in whole body bone mineral content (BMC, B = 0.88, p < 0.001), lumbar spine BMD (B = 0.79, p = 0.002), femoral neck BMD (B = 0.670, p = 0.009); fat mass index (B = 1.33, p = 0.003), and lean body mass index (LBMI, B = 1.10, p < 0.001) compared to AN, adjusting for age, sex, and duration of illness. A prior overweight history was associated with greater Z-scores in whole body BMC; lumbar spine BMD, total hip BMD, femoral neck BMD, and LBMI. Discussion Adolescents with AAN had higher BMD Z-scores than adolescents with AN; adolescents with a prior overweight history had greater BMD Z-scores than adolescents without a prior overweight history. These findings may inform clinical guidelines for the medical management of AAN.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available