Enhancing resilient property of Kaempferia galanga rhizome starch by succinylation

The present study investigates on the succinylation of native starch isolated from the rhizomes of Kaempferia galanga. Succinylated starch with different degree of substitution in the range of 0.030-0.189 was prepared using varying concentrations of succinic anhydride. Morphological study showed the formation of porous structure on the outer surface of the starch granules, whereas FTIR spectra showed the presence of ester group on the modified starches. With the increase in degree of substitution, there was an increased amylose content and less fraction of amylopectin and thereby modified starch samples showed relatively less water retention capacity and faster disintegration. The swelling and solubility power of native and modified starches were found to increase with increase in temperature. From the TGA analysis, the succinylated starches were found to be more thermally stable than native starch. In vitro drug release study also supports the disintegration pattern and proves the potential of succinylated Kaempferia galanga starch as resilient material in sustained-drug release systems. (C) 2018 Elsevier B.V. All rights reserved.