4.5 Review

Arterial Baroreflex Resetting During Exercise in Humans: Underlying Signaling Mechanisms

Journal

EXERCISE AND SPORT SCIENCES REVIEWS
Volume 47, Issue 3, Pages 129-141

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1249/JES.0000000000000190

Keywords

central command; exercise pressor reflex; cardiopulmonary baroreflex; reactive oxygen species; nitric oxide; exercise-induced hypertension

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The arterial baroreflex (ABR) resets during exercise in an intensity-dependent manner to operate around a higher blood pressure with maintained sensitivity. This review provides a historical perspective of ABR resetting and the involvement of other neural reflexes in mediating exercise resetting. Furthermore, we discuss potential underlying signaling mechanisms that may contribute to exercise ABR resetting in physiological and pathophysiological conditions.

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