4.5 Review

New Findings in Metal Complexes with Antiproliferative Activity Containing 1,3,5-Triaza-7-phosphaadamantane (PTA) and Derivative Ligands

Journal

EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
Volume -, Issue 11-12, Pages 1529-1538

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejic.201801426

Keywords

PTA; dmoPTA; Complexes; Antiproliferative activity; Cancer

Funding

  1. European Commission FEDER program [CTQ2015-67384-R]
  2. Junta de Andalucia PAI-research group [FQM-317]
  3. COST Action [CM1302]

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This minireview summarizes some of the most significant findings published in the last years on metal complexes containing PTA and PTA derivatives ligands such as dmoPTA, with antiproliferative activity [PTA = 1,3,5-triaza-7-phosphaadamantane; dmoPTA = 3,7-dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane (dmoPTA)]. Comments on other biological properties of the complexes are also included.

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