Journal
DEVELOPMENTAL CELL
Volume 48, Issue 5, Pages 595-596Publisher
CELL PRESS
DOI: 10.1016/j.devcel.2019.02.017
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How the products of transient hematopoiesis in the yolk sac, dorsal aorta, and developing heart tube function at their sites of production is poorly understood. In this issue of Developmental Cell, Shigeta et al. (2019) elegantly demonstrate that macrophages derived from the heart tube contribute to local tissue remodeling during valve development.
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