4.6 Review

Recent developments in Pickering emulsions for biomedical applications

Journal

CURRENT OPINION IN COLLOID & INTERFACE SCIENCE
Volume 39, Issue -, Pages 173-189

Publisher

ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.cocis.2019.01.017

Keywords

Pickering emulsions; Biomedicine; Stimuli-responsive; Therapeutic delivery

Funding

  1. Engineering and Physical Sciences Research Council through the Centre for Doctoral Training in Advanced Therapeutics and Nanomedicines [EP/L01646X]
  2. Centre for Doctoral Training in Molecular Modelling and Materials Science [EP/L015862/1]

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Pickering emulsions, stabilised by organic or inorganic particles, offer long-term dispersibility of liquid droplets and resistance to coalescence. The versatility of stabilising particles and their ability to encapsulate and release cargo with high internal payload capacity makes them attractive in a wide variety of applications, ranging from catalysis to the cosmetic and food industry, While these properties make them an equally promising material platform for pharmaceutical and clinical applications, the development of Pickering emulsions for healthcare is still in its infancy. Herein, we summarise and discuss recent progress in the development of Pickering emulsions for biomedical applications, probing their design for passive diffusion-based release as well as stimuli-responsive destabilisation. We further comment on challenges and future directions of this exciting and rapidly expanding area of research.

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