Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 55, Issue -, Pages 134-150Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2018.09.010
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Funding
- ERG (FP7/2007-2013/ERC [306385 Sof1]
- Region Aquitaine
- French Government Investments for the Future Programme, University of Bordeaux Initiative of Excellence (iDEX Bordeaux) [(ANR)-10-IDEX-03-02]
- Institut Universitaire de France
- University of Bordeaux
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Plankton produces numerous chemical compounds used in cosmetics and functional foods. They also play a key role in the carbon budget on the Earth. In a context of global change, it becomes important to understand the physiological response of these microorganisms to changing environmental conditions. Their adaptations and the response to specific environmental conditions are often restricted to a few active cells or individuals in large populations. Using analytical capabilities at the subnanoliter scale, microfluidic technology has also demonstrated a high potential in biological assays. Here, we review recent advances in microfluidic technologies to overcome the current challenges in high content analysis both at population and the single cell level.
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