4.6 Review

Synthesis, Biological Activity and Medicinal Applications of Ruthenium Complexes Containing Carbohydrate Ligands

Journal

CURRENT MEDICINAL CHEMISTRY
Volume 26, Issue 35, Pages 6412-6437

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/0929867326666190124124350

Keywords

Ruthenium; carbohydrates; nucleolipidic complexes; polypyridyl complexes; arene complexes; cyclopentadienyl complexes; tricarbonyl complexes

Funding

  1. Fundacao para a Ciencia e Tecnologia [UID/QUI/00100/2013]
  2. FCT [IF/00849/2012]

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The search for new metal-efficient drugs has attracted considerable attention of the scientific community. Among them, ruthenium complexes have emerged as an excellent alternative of platinum complexes. This review presents a thorough and timely coverage of the synthesis, biological activity and medicinal applications of ruthenium complexes bearing carbohydrate ligands, allowing a large community of readers, in particularly the community that works in organic, inorganic, bioorganometallic and medicinal chemistry, ready access to the most relevant examples.

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