Journal
COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING
Volume 22, Issue 3, Pages 331-339Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10255842.2018.1555584
Keywords
Computational fluid dynamics; voxel-based simulation; human nasal cavity
Funding
- JSPS KAKENHI [26630059]
- JSPS Bilateral Program
- RIKEN Advanced Institute for Computational Science through the HPCI System Research project [hp160186]
- BBSRC [BB/E023444/1] Funding Source: UKRI
- Grants-in-Aid for Scientific Research [26630059] Funding Source: KAKEN
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This paper describes the simulation of airflow in human nasal airways using voxel-based modeling characterized by robust, automatic, and objective grid generation. Computed tomography scans of a healthy adult nose are used to reconstruct 3D virtual models of the nasal airways. Voxel-based simulations of restful inspiratory flow are then performed using various mesh sizes to determine the level of granularity required to adequately resolve the airflow. For meshes with close voxel spacings, the model successfully reconstructs the nasal structure and predicts the overall pressure drop through the nasal cavity.
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