4.4 Review

Pharmacology, Pharmacokinetics and Pharmacodynamics of Eculizumab, and Possibilities for an Individualized Approach to Eculizumab

Related references

Note: Only part of the references are listed.
Review Urology & Nephrology

The renaissance of complement therapeutics

Daniel Ricklin et al.

NATURE REVIEWS NEPHROLOGY (2018)

Article Transplantation

Safety and effectiveness of restrictive eculizumab treatment in atypical haemolytic uremic syndrome

Kioa L. Wijnsma et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2018)

Review Pharmacology & Pharmacy

Eculizumab: A Review in Generalized Myasthenia Gravis

Sohita Dhillon

DRUGS (2018)

Article Biochemical Research Methods

The impact of eculizumab on routine complement assays

Maria A. Willrich et al.

JOURNAL OF IMMUNOLOGICAL METHODS (2018)

Review Multidisciplinary Sciences

Myasthenia gravis: the role of complement at the neuromuscular junction

James F. Howard

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2018)

Article Immunology

Monitoring of complement activation biomarkers and eculizumab in complement-mediated renal disorders

C. Wehling et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2017)

Article Urology & Nephrology

Pathogenic Variants in Complement Genes and Risk of Atypical Hemolytic Uremic Syndrome Relapse after Eculizumab Discontinuation

Fadi Fakhouri et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)

Article Oncology

Eculizumab treatment: stochastic occurrence of C3 binding to individual PNH erythrocytes

Michela Sica et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)

Article Clinical Neurology

Inhibition of complement in Guillain-Barre syndrome: the ICA-GBS study

Amy I. Davidson et al.

JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM (2017)

Review Medicine, General & Internal

Haemolytic uraemic syndrome

Fadi Fakhouri et al.

LANCET (2017)

Review Rheumatology

Expanding the therapeutic options for renal involvement in lupus: eculizumab, available evidence

Savino Sciascia et al.

RHEUMATOLOGY INTERNATIONAL (2017)

Article Pharmacology & Pharmacy

Eculizumab Dosing Regimen in Atypical HUS: Possibilities for Individualized Treatment

E. Volokhina et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2017)

Review Hematology

Complementopathies

Andrea C. Baines et al.

BLOOD REVIEWS (2017)

Review Hematology

Management of thrombosis in paroxysmal nocturnal hemoglobinuria: a clinician's guide

Morag Griffin et al.

THERAPEUTIC ADVANCES IN HEMATOLOGY (2017)

Article Urology & Nephrology

Efficacy and safety of eculizumab in childhood atypical hemolytic uremic syndrome in Japan

Naoko Ito et al.

CLINICAL AND EXPERIMENTAL NEPHROLOGY (2016)

Article Clinical Neurology

Therapy with eculizumab for patients with CD59 p.Cys89Tyr mutation

Dror Mevorach et al.

ANNALS OF NEUROLOGY (2016)

Article Pharmacology & Pharmacy

Off-label use of the expensive orphan drug eculizumab in France 2009-2013 and the impact of literature: focus on the transplantation field

Johann Castaneda-Sanabria et al.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2016)

Article Hematology

Interim analysis of post-marketing surveillance of eculizumab for paroxysmal nocturnal hemoglobinuria in Japan

Haruhiko Ninomiya et al.

INTERNATIONAL JOURNAL OF HEMATOLOGY (2016)

Letter Hematology

Genetic variants of C5 and polymorphisms of C3 in Chinese patients with paroxysmal nocturnal hemoglobinuria

Y. Du et al.

INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY (2016)

Article Immunology

Structural Basis for Eculizumab-Mediated Inhibition of the Complement Terminal Pathway

Janus Asbjorn Schatz-Jakobsen et al.

JOURNAL OF IMMUNOLOGY (2016)

Article Urology & Nephrology

Eculizumab is a safe and effective treatment in pediatric patients with atypical hemolytic uremic syndrome

Larry A. Greenbaum et al.

KIDNEY INTERNATIONAL (2016)

Article Transplantation

Atypical haemolytic uraemic syndrome and pregnancy: outcome with ongoing eculizumab

Aude Servais et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2016)

Review Transplantation

Update on C3 glomerulopathy

Thomas D. Barbour et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2016)

Article Urology & Nephrology

Eculizumab for Treatment of Rapidly Progressive C3 Glomerulopathy

Moglie Le Quintrec et al.

AMERICAN JOURNAL OF KIDNEY DISEASES (2015)

Letter Urology & Nephrology

Discontinuation of Eculizumab Treatment in Atypical Hemolytic Uremic Syndrome: An Update

Gianluigi Ardissino et al.

AMERICAN JOURNAL OF KIDNEY DISEASES (2015)

Article Hematology

Management of pregnancy in paroxysmal nocturnal hemoglobinuria on long-term eculizumab

Marie-Christiane Vekemans et al.

BLOOD COAGULATION & FIBRINOLYSIS (2015)

Article Urology & Nephrology

Eculizumab in Pediatric Dense Deposit Disease

Michiel J. S. Oosterveld et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2015)

Article Medicine, Research & Experimental

Therapeutic drug monitoring of eculizumab: Rationale for an individualized dosing schedule

Philippe Gatault et al.

Review Biochemistry & Molecular Biology

Atypical aHUS: State of the art

Carla M. Nester et al.

MOLECULAR IMMUNOLOGY (2015)

Article Medicine, General & Internal

Eculizumab in Pregnant Patients with Paroxysmal Nocturnal Hemoglobinuria

Richard J. Kelly et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Pediatrics

Eculizumab hepatotoxicity in pediatric aHUS

Wesley Hayes et al.

PEDIATRIC NEPHROLOGY (2015)

Article Transplantation

Outbreak of Escherichia coli O104:H4 haemolytic uraemic syndrome in France: outcome with eculizumab

Yahsou Delmas et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2014)

Article Medicine, General & Internal

Genetic Variants in C5 and Poor Response to Eculizumab

Jun-ichi Nishimura et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Review Immunology

Hemolytic uremic syndrome

Caterina Mele et al.

SEMINARS IN IMMUNOPATHOLOGY (2014)

Article Medicine, General & Internal

Terminal Complement Inhibitor Eculizumab in Atypical Hemolytic-Uremic Syndrome

C. M. Legendre et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Obstetrics & Gynecology

Eculizumab for Atypical Hemolytic Uremic Syndrome in Pregnancy

Gianluigi Ardissino et al.

OBSTETRICS AND GYNECOLOGY (2013)

Article Urology & Nephrology

Eculizumab for Dense Deposit Disease and C3 Glomerulonephritis

Andrew S. Bomback et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2012)

Review Urology & Nephrology

Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies

Julien Zuber et al.

NATURE REVIEWS NEPHROLOGY (2012)

Letter Medicine, General & Internal

Eculizumab for the Treatment of Dense-Deposit Disease

Marina Vivarelli et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Article Clinical Neurology

An open label clinical trial of complement inhibition in multifocal motor neuropathy

Amanda M. Fitzpatrick et al.

JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM (2011)

Article Hematology

The management of pregnancy in paroxysmal nocturnal haemoglobinuria on long term eculizumab

Richard Kelly et al.

BRITISH JOURNAL OF HAEMATOLOGY (2010)

Review Pharmacology & Pharmacy

Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies

Ron J. Keizer et al.

CLINICAL PHARMACOKINETICS (2010)

Article Medicine, General & Internal

The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria

Peter Hillmen et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

Article Medicine, General & Internal

Effect of eculizumab on hemolysis and transfusion requirements in patients with paroxysmal nocturnal hemoglobinuria

P Hillmen et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)