4.2 Article

Should Children With Constipation Undergo Blood Lead Level Screening?

Journal

CLINICAL PEDIATRICS
Volume 58, Issue 6, Pages 627-632

Publisher

SAGE PUBLICATIONS INC
DOI: 10.1177/0009922819832029

Keywords

constipation; lead poisoning; diagnosis; retrospective studies; pediatrics

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Funding

  1. National Institutes of Health [UL1-TR-001857]

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This study aimed to compare the prevalence of elevated blood lead level in children with constipation to the population prevalence. We reviewed the charts of 441 children who were screened with a blood lead level on presenting to the gastroenterology clinic at UPMC Children's Hospital of Pittsburgh for evaluation of constipation. The prevalence of blood lead level greater than 5 mu g/dL was 1.36% (6/441; 95% confidence interval = 1.23% to 1.49%), which is significantly lower than the 4.01% prevalence in the population reported by the Center for Disease Control and Prevention. No patients had a blood lead level greater than 10 mu g/dL. Age under 5 years old showed an increased odds of lead level greater than 5 mu g/dL (odds ratio = 7.5; 95% confidence interval = 1.2 to 47.3, P < .05). We concluded that children seen in the gastroenterology clinic for constipation are unlikely to have an elevated blood lead level on routine screening.

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