Journal
CHIRALITY
Volume 31, Issue 4, Pages 328-335Publisher
WILEY
DOI: 10.1002/chir.23059
Keywords
amino acids; axial chirality; chiral HPLC; kinetic of racemization; rotational energy barriers
Funding
- Basque Foundation for Science
- IKERBASQUE
- National Natural Science Foundation of China [21761132021]
- Changzhou Jin-Feng-Huang program
Ask authors/readers for more resources
Herein, we disclose the design of a model Ni(II) complex of glycine Schiff base possessing single-nitrogen stereogenic center, which was successfully used for high-performance liquid chromatography (HPLC)-assisted assessment of its configurational stability. The major finding is that the configurational stability of the Ni(II)-coordinated nitrogen is profoundly dependent on the reaction conditions used, in particular the solvent, and can range from inconsequential (t(1/2) less than 5 min) to virtually completely stable (t(1/2) 90 y). The discovery reported in this study most likely to be of certain theoretical and synthetic value.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available