Manganese-Catalyzed ortho-Alkenylation of Aromatic Amidines with Alkynes via C-H Activation

The first ortho-alkenylation of aromatic amidines with alkynes was realized by earth-abundant manganese catalysis through C-H activation. A catalytic amount of PhMgBr was found essential for improved efficiency of this transformation. Wide tolerance of functional groups and excellent E/Z selectivity highlighted the current protocol.