Related references
Note: Only part of the references are listed.Paving TRAIL's Path with Ubiquitin
Elodie Lafont et al.
TRENDS IN BIOCHEMICAL SCIENCES (2018)
BRAF and AXL oncogenes drive RIPK3 expression loss in cancer
Ayaz Najafov et al.
PLOS BIOLOGY (2018)
Superior Properties of Fc-comprising scTRAIL Fusion Proteins
Meike Hutt et al.
MOLECULAR CANCER THERAPEUTICS (2017)
Targeted agents and immunotherapies: optimizing outcomes in melanoma
Jason J. Luke et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2017)
TNFα blockade overcomes resistance to anti-PD-1 in experimental melanoma
Florie Bertrand et al.
NATURE COMMUNICATIONS (2017)
Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis
Jiefei Geng et al.
NATURE COMMUNICATIONS (2017)
2-HG Inhibits Necroptosis by Stimulating DNMT1-Dependent Hypermethylation of the RIP3 Promoter
Zhentao Yang et al.
CELL REPORTS (2017)
TAK-ing aim at chemoresistance: The emerging role of MAP3K7 as a target for cancer therapy
Raffaela Santoro et al.
DRUG RESISTANCE UPDATES (2017)
The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death
Elodie Lafont et al.
EMBO JOURNAL (2017)
TAK1 regulates caspase 8 activation and necroptotic signaling via multiple cell death checkpoints
Xiaoyun Guo et al.
CELL DEATH & DISEASE (2016)
Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics
Gi-Bang Koo et al.
CELL RESEARCH (2015)
TAK1 selective inhibition: state of the art and future opportunities
Iain Kilty et al.
FUTURE MEDICINAL CHEMISTRY (2015)
Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib
Caroline Robert et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Absence of RIPK3 predicts necroptosis resistance in malignant melanoma
P. Geserick et al.
CELL DEATH & DISEASE (2015)
Molecular crosstalk between apoptosis, necroptosis, and survival signaling
Tom Vanden Berghe et al.
MOLECULAR & CELLULAR ONCOLOGY (2015)
TAK1 control of cell death
S. R. Mihaly et al.
CELL DEATH AND DIFFERENTIATION (2014)
Molecular Pathways: Targeting Inhibitor of Apoptosis Proteins in Cancer-From Molecular Mechanism to Therapeutic Application
Simone Fulda
CLINICAL CANCER RESEARCH (2014)
Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3
Huayi Wang et al.
MOLECULAR CELL (2014)
The Immune Microenvironment Confers Resistance to MAPK Pathway Inhibitors through Macrophage-Derived TNFα
Michael P. Smith et al.
CANCER DISCOVERY (2014)
Mechanism and In Vitro Pharmacology of TAK1 Inhibition by (5Z)-7-Oxozeaenol
Jiaquan Wu et al.
ACS CHEMICAL BIOLOGY (2013)
RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition
Y. Dondelinger et al.
CELL DEATH AND DIFFERENTIATION (2013)
Cutoff Finder: A Comprehensive and Straightforward Web Application Enabling Rapid Biomarker Cutoff Optimization
Jan Budczies et al.
PLOS ONE (2012)
Targeting of TAK1 in inflammatory disorders and cancer
Hiroaki Sakurai
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data
Ethan Cerami et al.
CANCER DISCOVERY (2012)
Targeting of 5-aza-2'-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme
Katan Patel et al.
NUCLEIC ACIDS RESEARCH (2010)
TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells
Griselda Herrero-Martin et al.
EMBO JOURNAL (2009)
Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment
Peter Geserick et al.
JOURNAL OF CELL BIOLOGY (2009)
TAK1 kinase determines TRAIL sensitivity by modulating reactive oxygen species and cIAP
S. Morioka et al.
ONCOGENE (2009)
Apoptosis: controlled demolition at the cellular level
Rebecca C. Taylor et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain
Shanshan Feng et al.
CELLULAR SIGNALLING (2007)
Distinct signaling pathways in TRAIL- versus tumor necrosis factor-induced apoptosis
Zhaoyu Jin et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
TNF-α in cancer treatment:: Molecular insights, antitumor effects, and clinical utility
Remco van Horssen et al.
ONCOLOGIST (2006)
Melanoma cells secrete follistatin, an antagonist of activin-mediated growth inhibition
C Stove et al.
ONCOGENE (2004)
A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses
FKM Chan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The role of chemokines in melanoma tumor growth and metastasis
AS Payne et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2002)