Journal
BRITISH JOURNAL OF ANAESTHESIA
Volume 123, Issue 1, Pages E16-E28Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.bja.2019.01.027
Keywords
antibiotics; blood products; chlorhexidine; latex; neuromuscular blocking agents; perioperative anaphylaxis; perioperative hypersensitivity; sugammadex
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Suspected perioperative hypersensitivity reactions are rare but contribute significantly to the morbidity and mortality of surgical procedures. Recent publications have highlighted the differences between countries concerning the respective risk of different drugs, and changes in patterns of causal agents and the emergence of new allergens. This review summarises recent information on the epidemiology of perioperative hypersensitivity reactions, with specific consideration of differences between geographic areas for the most frequently involved offending agents.
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