4.7 Article

Tumor-educated platelets

Journal

BLOOD
Volume 133, Issue 22, Pages 2359-2364

Publisher

AMER SOC HEMATOLOGY
DOI: 10.1182/blood-2018-12-852830

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Funding

  1. European Research Council [H2020-MSCA 765492, 713727, 336540]
  2. Netherlands Organisation for Scientific Research [91711366]
  3. Dutch Cancer Society [VU2015-8080]
  4. European Research Council (ERC) [713727] Funding Source: European Research Council (ERC)

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Liquid biopsies have been considered the holy grail in achieving effective cancer management, with blood tests offering a minimally invasive, safe, and sensitive alternative or complementary approach for tissue biopsies. Currently, blood-based liquid biopsy measurements focus on the evaluation of biomarker types, including circulating tumor DNA, circulating tumor cells, extracellular vesicles (exosomes and oncosomes), and tumor-educated platelets (TEPs). Despite the potential of individual techniques, each has its own advantages and disadvantages. Here, we provide further insight into TEPs.

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