Journal
BIOINFORMATICS
Volume 35, Issue 21, Pages 4392-4393Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btz232
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Funding
- Research Council of Norway [230338]
- Stiftelsen K.G. Jebsen
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A Summary: Data from chromatin immunoprecipitation (ChIP) followed by high-throughput sequencing (ChIP-seq) generally contain either narrow peaks or broad and diffusely enriched domains. The SICER ChIP-seq caller has proven adept at finding diffuse domains in ChIP-seq data, but it is slow, requires much memory, needs manual installation steps and is hard to use. epic2 is a complete rewrite of SICER that is focused on speed, low memory overhead and ease-of-use.
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