Journal
BIOCONJUGATE CHEMISTRY
Volume 30, Issue 3, Pages 531-535Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.bioconjchem.8b00868
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Funding
- EPSRC ICASE award [EP/L505729/I]
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The rapid surface immobilization of protein on monodispersed polyester microcarriers is reported. A model protein, functionalized with a dibenzocyclooctyne core, immobilizes on the surface of azide-terminal polycaprolactone microcarriers within 10 min compared to 12 h for other conjugation techniques, and it is conducted in physiological conditions and in the absence of coupling reagents.
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