Journal
ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY
Volume 102, Issue 3, Pages -Publisher
WILEY
DOI: 10.1002/arch.21547
Keywords
Bacillus thuringiensis; cross-resistance; pyramided Bt crops; resistance mechanism
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Bt crop pyramids produce two or more Bt proteins active to broaden the spectrum of action and to delay the development of resistance in exposed insect populations. The cross-resistance between Bt toxins is a vital restriction factor for Bt crop pyramids, which may reduce the effect of pyramid strategy. In this review, the status of the cross-resistance among more than 20 Bt toxins that are most commonly used against 13 insect pests was analyzed. The potential mechanisms of cross-resistance are discussed. The corresponding measures, including pyramid RNA interference and Bt toxin, high dose/refuge, and so on are advised to be taken for adopting the pyramided strategy to delay the Bt evolution of resistance and control the target pest insect.
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