Journal
ANALYTICAL CHEMISTRY
Volume 91, Issue 5, Pages 3754-3758Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.analchem.9b00199
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [21427808, 21375077]
- Fundamental Research Funds of Shandong University [2018JC017]
Ask authors/readers for more resources
For the screening of novel toxic-element-free and biocompatible electrochemiluminophores, electrochemiluminescence (ECL) of multinary nanocrystals (NCs) was investigated for the first time with Zn Ag In S (ZAIS) NCs as model. Aqueous soluble ZAIS NCs could bring out efficient reductive-oxidation ECL with tri-n-propylamine as coreactant, while coating the ZAIS NCs with a ZnS shell could reduce the surface defects of ZAIS NCs, and enable 6.7-fold enhanced ECL of ZAIS/ZnS NCs as compared to ZAIS NCs. ECL of ZAIS/ZnS NCs was about 4.2-fold that of ternary CuInS2/ZnS NCs, spectrally similar to that of Ru(bpy)(3)(2+) with maximum emission around 605 nm, and favorable for less electrochemical interference with a lowered triggering potential (similar to 0.95 V) than that of Ru(bpy)(3)(2+). An ultrasensitive ECL microRNA sensor was fabricated with ZAIS/ZnS NCs as tags, which could sensitively and selectively determine microRNA-141 with a wide linearity range from 0.1 fmol/L to 20 pmol/L and a low limit of detection at 50 amol/L (S/N = 3). Multinary NCs might provide a promising alternative to the traditional binary NCs for both electrochemiluminophore screening and NC ECL modulating.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available