Journal
BIOINFORMATICS
Volume 31, Issue 12, Pages 2043-2045Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btv083
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Funding
- Deutsche Forschungsgemeinschaft [MU3613/1-1, MU3613/3-1, SFB 1064 TP A7]
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Protein crosslinking has been used for decades to derive structural information about proteins and protein complexes. Only recently, however, it became possible to map the amino acids involved in the crosslinks with the advent of high resolution mass spectrometry (MS). Here, we present Crossfinder, which automates the search for crosslinks formed by site-specifically incorporated crosslinking amino acids in LC-MS-MS data.
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