Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 358, Issue 5, Pages 816-819Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201500822
Keywords
arylacetonitriles; alpha-benzylation; benzylic alcohol derivatives; C-O activation; nickel
Categories
Funding
- NSFC [21373080, 21403062]
- HNNSF [2015JJ3039]
- Fundamental Research Funds for the Central Universities (Hunan University)
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Efficient Ni-catalyzed direct cross-couplings of benzylic alcohol derivatives with arylacetonitriles via C-O activation are described. Various alpha-benzylated arylacetonitriles including those with functional groups can be prepared under mild reaction conditions.
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