Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 359, Issue 4, Pages 698-708Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201600855
Keywords
Carbene insertion; N-tosylhydrazones; Transition-metal-free; Thioacetals; Selenoacetals
Categories
Funding
- IIT Madras [CHY/15-16/836/RFRI/GSEK]
- CSIR, New Delhi
Ask authors/readers for more resources
A transition-metal-free and base-mediated carbene insertion across sulfur-sulfur and selenium-selenium bonds has been developed by employing N-tosylhydrazone as a stable and safe carbene precursor. The ylide formation from carbene followed by Stevens rearrangement are considered to be the key steps. This thiol and selenol-free protocol delivers thioacetals and selenoacetals in good to excellent yields in short reaction time with good functional group tolerance. A one-pot synthesis involving insitu generation of tosylhydrazone has also been demonstrated.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available