Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 358, Issue 23, Pages 3840-3846Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201600700
Keywords
alkylamination; C-H functionalization; iron catalysis; phenols; synthetic methods
Categories
Funding
- National Natural Science Foundation of China [21321061, 21072134, J1103315/J0104]
- Applied Basic Research Foundation of Sichuan Province
Ask authors/readers for more resources
A novel iron-catalyzed direct alkylamination reaction of phenols has been achieved with O-benzoyl-N-alkylhydroxylamines as aminating agents. This protocol provides a facile access to N-alkyl-substituted aminophenols though a radical reaction from phenols. The catalytic direct alkylamination operates at room temperature without the need of any ligands and additives to afford the desired products with excellent regioselectivity and functional group tolerance.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available