4.7 Article

N-Heterocyclic Carbene-Catalyzed Synthesis of Multi-Substituted Benzenes from Enals and α-Cyano-β-methylenones

Journal

ADVANCED SYNTHESIS & CATALYSIS
Volume 358, Issue 18, Pages 2862-2866

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201600531

Keywords

annulation; benzene; carbene; enal; organocatalysis

Funding

  1. National Natural Science Foundation of China [21425207, 21521002]
  2. Chinese Academy of Sciences

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An oxidative NHC-catalyzed [2+4] annulation of enals and alpha-cyano-beta-methylenones was established for the rapid assembly of multi-substituted benzenes.

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