Journal
ADVANCED MATERIALS
Volume 29, Issue 5, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201601776
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Funding
- International S&T Cooperation Program of China (ISTCP) [2015DFA50310]
- National Natural Science Foundation of China [51373079, 51403159]
- Program for Changjiang Scholars and Innovative Research Team in University [IRT13023]
- National Young Top-notch Talent Program
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A novel vaccine adjuvant based on a supra-molecular hydrogel of a D-tetrapeptide is reported. Antigens can be easily incorporated into the hydrogel by a vortex or by gently shaking before injection. The vaccines can stimulate strong CD8+ T-cell responses, which significantly inhibits tumor growth. This novel adjuvant is expected to enable a wide range of sub-unit vaccines and help the production of antibodies.
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