Journal
ADVANCED MATERIALS
Volume 28, Issue 38, Pages 8524-8530Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201602373
Keywords
chlorophyll; frozen micelles; gut imaging; multimodal imaging; pheophytin
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Funding
- National Institutes of Health [DP5OD0178980, 1R01CA169365, P30CA014520]
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Edible, surfactant-stripped, frozen micelles are formed from pheophytin (demetallated chlorophyll), a pigment that is naturally consumed in human diets. Pheophytin nanoparticles pass completely and safely through the gastrointestinal tract and enable trimodal gut contrast imaging via photoacoustic, fluorescence, and positron emission tomography techniques.
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