4.8 Article

Morphology-Tailoring of a Red AIEgen from Microsized Rods to Nanospheres for Tumor-Targeted Bioimaging

Journal

ADVANCED MATERIALS
Volume 28, Issue 16, Pages 3187-3193

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201504782

Keywords

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Funding

  1. National 973 Program [2012CB933602, 2013CB733700]
  2. NSFC/China
  3. NSFC for Creative Research Groups [21421004]
  4. NSFC for Distinguished Young Scholars [21325625]
  5. 111 project [B14018]
  6. Oriental Scholarship, Shanghai Pujiang Program [13PJD010]
  7. Fundamental Research Funds for the Central Universities

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Efficient morphology modulation of a red AIEgen from pristine microsized rods to nanospheres is achieved via encapsulating QM-2 (quinoline-malononitrile-2) into hybrid micelles. This novel reagent shows great potential in tumor-targeted bioimaging because of its monodispersion in aqueous systems, the uniform diameter of approximate to 30 nm, enhanced fluorescence brightness with a large Stokes shift of 190 nm, and strongly increased biocompatibility and photostability.

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