Journal
ADVANCED MATERIALS
Volume 28, Issue 21, Pages 4032-4039Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201505723
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Funding
- Dutch Institute for Regenerative Medicine (NIRM)
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Material-free tissues are assembled using solely cells. Microstructured hydrogel templates and high content screening allow the formation of centimeter-scale tissues with precise architectures. Similar to developing tissues, these contract autonomously, controllably shift shape, self-scaffold by secreting extracellular matrix, and undergo morphogenesis.
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