Journal
ADVANCED MATERIALS
Volume 28, Issue 38, Pages 8511-8518Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201600773
Keywords
cancer; controlled drug release; DNA assembly; gold nanorods; core-satellite; nanotechnology; nanomedicine
Categories
Funding
- Canadian Institute of Health Research [MOP-130143, RMF-111623O]
- Natural Sciences and Engineering Research Council (NSERC) [2015-06397]
- Prostate Cancer Foundation [D2014-12]
- Canadian Breast Cancer Foundation
- NSERC
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The use of DNA to assemble inorganic nanoparticles into superstructures is an emerging strategy to build non-toxic delivery vehicles for targeting diseases in the body. The impact of the core-satellite nanosystem design in mediating drug storage, drug release (via heat), and killing of HeLa cells in culture is investigated.
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