4.8 Article

Near-Infrared Upconversion Chemodosimeter for In Vivo Detection of Cu2+ in Wilson Disease

Journal

ADVANCED MATERIALS
Volume 28, Issue 31, Pages 6625-+

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201601140

Keywords

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Funding

  1. National Basic Research Program of China [2015CB931800, 2012CB932403]
  2. National Science Foundation of China [21231004, 21375024]
  3. China Postdoctoral Science Foundation [2015M571482]
  4. CAS/SAFEA International Partnership Program for Creative Research Teams

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Near-infrared upconversion chemodosimetry is a promising detection method by virtue of the frequency upconversion technique, which shows very high sensitivity and selectivity for the detection of Cu2+ ions in vitro and in vivo. This method offers a new opportunity for non-invasive diagnosis of Wilson disease associated with Cu2+ detection in clinical medicine.

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