Journal
ELECTRONICS
Volume 8, Issue 1, Pages -Publisher
MDPI
DOI: 10.3390/electronics8010034
Keywords
Laboratory animal transportation; EPIC sensors; mice stress; physiological signal processing; noninvasive measurements; hardware implementation
Categories
Funding
- State Chancellery of the federal state Saarland (Germany) [C/1-LdZ-2011]
- Spanish Government (Ministerio de Economia y Competitividad) [DPI2016-80391-C3-3-R]
- DFG [SCH682/3-1, CIG303682]
- FNR CORE (Itgb3VascIn)
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Laboratory mice are used in biomedical research as models for studying human disease. These mice may be subject to significant levels of stress during transportation that can cause alterations that could negatively affect the results of the performed investigation. Here, we present the design and realization of a prototypical transportation container for laboratory mice, which may contribute to improved laboratory animal welfare. This prototype incorporates electric potential integrated circuit (EPIC) sensors, which have been shown to allow the recording of physiological parameters (heart rate and breathing rate) and other sensors for recording environmental parameters during mouse transportation. This allows for the estimation of the stress levels suffered by mice. First experimental results for capturing physiological and environmental parameters are shown and discussed.
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