4.4 Article

Canary in the Coal Mine? Transmitted Mutations Conferring Resistance to All Integrase Strand Transfer Inhibitors in a Treatment-Naive Patient

Journal

OPEN FORUM INFECTIOUS DISEASES
Volume 5, Issue 11, Pages -

Publisher

OXFORD UNIV PRESS INC
DOI: 10.1093/ofid/ofy294

Keywords

HIV; integrase; transmitted resistance; treatment naive

Funding

  1. NIAID NIH HHS [P30 AI050410] Funding Source: Medline

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Transmitted drug resistance to the integrase strand transfer inhibitor (INSTI) class of antiretrovirals is very rare. We present a case of a treatment-naive female patient with human immunodeficiency virus harboring resistance to all INSTIs, including bictegravir and dolutegravir.

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