Journal
PHARMACEUTICS
Volume 10, Issue 4, Pages -Publisher
MDPI
DOI: 10.3390/pharmaceutics10040191
Keywords
solid lipid nanoparticles; cytotoxicity; targeted drug delivery; colloidal nanocarriers
Categories
Funding
- Academy of Finland [309374, 309794]
- Academy of Finland (AKA) [309794, 309794] Funding Source: Academy of Finland (AKA)
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Solid lipid nanoparticles (SLNs) are nanocarriers developed as substitute colloidal drug delivery systems parallel to liposomes, lipid emulsions, polymeric nanoparticles, and so forth. Owing to their unique size dependent properties and ability to incorporate drugs, SLNs present an opportunity to build up new therapeutic prototypes for drug delivery and targeting. SLNs hold great potential for attaining the goal of targeted and controlled drug delivery, which currently draws the interest of researchers worldwide. The present review sheds light on different aspects of SLNs including fabrication and characterization techniques, formulation variables, routes of administration, surface modifications, toxicity, and biomedical applications.
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