Journal
ADVANCED MATERIALS TECHNOLOGIES
Volume 4, Issue 6, Pages -Publisher
WILEY
DOI: 10.1002/admt.201800625
Keywords
microfluidics; point-of-care testing; reagents; release; storage
Categories
Funding
- Chinese Academy of Sciences [121D11KYSB20170026]
- National Natural Science Foundation of China [21535001, 81730051, 21761142006, 81671784, 21505027]
- [2017YFA0205901]
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Microfluidics has emerged as a useful material for point-of-care testing. However, conventional microfluidic devices rely on multiple steps to complete the detection process, which may not be acceptable for untrained users. The emerging self-contained point-of-care devices, with all necessary reagents prestored in, address this limitation. This paper summarizes the recent advances of self-contained point-of-care devices, with emphasis on the approaches for reagents integration and manipulation. Due to the intrinsic similarity and relevance of these approaches in pharmaceutical applications, several examples about drug delivery in vivo are presented. Different approaches are compared and future trends for the development of self-contained point-of-care devices are outlined.
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