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HUMAN MOLECULAR GENETICS (2006)
p16INK4A is a robust in vivo biomarker of cellular aging in human skin
Sigrun Ressler et al.
AGING CELL (2006)
The laminopathies: a clinical review
J. Rankin et al.
CLINICAL GENETICS (2006)
Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting γ-H2AX induction
Ji-Hye Park et al.
EMBO JOURNAL (2006)
p21Waf1/Cip1 plays a critical role in modulating senescence through changes of DNA methylation
Quan Hui Zheng et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2006)
Inactivation of p16INK4a (inhibitor of cyclin-dependent kinase 4A) immortalizes primary human keratinocytes by maintaining cells in the stem cell compartment
Riccardo Maurelli et al.
FASEB JOURNAL (2006)
Cockayne syndrome group B protein (CSB) plays a general role in chromatin maintenance and remodeling
John C. Newman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging
Dale K. Shumaker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Lamin A-dependent nuclear defects in human aging
P Scaffidi et al.
SCIENCE (2006)
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
R Mostoslavsky et al.
CELL (2006)
Regulation of growth arrest in senescence: Telomere damage is not the end of the story
U Herbig et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2006)
Temporally controlled targeted somatic mutagenesis in embryonic surface ectoderm and fetal epidermal keratinocytes unveils two distinct developmental functions of BRG1 in limb morphogenesis and skin barrier formation
AK Indra et al.
DEVELOPMENT (2005)
Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation
I Varela et al.
NATURE (2005)
p63 deficiency activates a program of cellular senescence and leads to accelerated aging
WM Keyes et al.
GENES & DEVELOPMENT (2005)
Lsh, a guardian of heterochromatin at repeat elements
K Muegge
BIOCHEMISTRY AND CELL BIOLOGY (2005)
Epigenetic differences arise during the lifetime of monozygotic twins
MF Fraga et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome
P Scaffidi et al.
NATURE MEDICINE (2005)
Fibroblast clones from patients with Hutchinson-Gilford progeria can senesce despite the presence of telomerase
CV Wallis et al.
EXPERIMENTAL GERONTOLOGY (2004)
Ataxia-telangiectasia-like disorder (ATLD) - its clinical presentation and molecular basis
AMR Taylor et al.
DNA REPAIR (2004)
Seckel syndrome exhibits cellular features demonstrating defects in the ATR-signalling pathway
GK Alderton et al.
HUMAN MOLECULAR GENETICS (2004)
Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome
RD Goldman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Matrix metalloproteinase-1 production observed after solar-simulated radiation exposure is assumed by dermal fibroblasts but involves a paracrine activation through epidermal keratinocytes
D Fagot et al.
PHOTOCHEMISTRY AND PHOTOBIOLOGY (2004)
A DNA damage checkpoint response in telomere-initiated senescence
FD di Fagagna et al.
NATURE (2003)
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
M Narita et al.
CELL (2003)
Ectopic expression of Kruppel like factor 4 (Klf4) accelerates formation of the epidermal permeability barrier
J Jaubert et al.
DEVELOPMENT (2003)
Mechanisms of photoaging and chronological skin aging
GJ Fisher et al.
ARCHIVES OF DERMATOLOGY (2002)
REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species
LW Ellisen et al.
MOLECULAR CELL (2002)
Postsynthetic trimethylation of histone H4 at lysine 20 in mammalian tissues is associated with aging
B Sarg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Human ING1 proteins differentially regulate histone acetylation
D Vieyra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Photoaging - Pathogenesis, prevention, and treatment
SW Kang et al.
CLINICS IN GERIATRIC MEDICINE (2001)
p63 identifies keratinocyte stem cells
G Pellegrini et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)