Journal
ADVANCED DRUG DELIVERY REVIEWS
Volume 105, Issue -, Pages 255-274Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.addr.2016.03.007
Keywords
Graphene; Graphene oxide; Graphene-based materials; Tissue engineering; Regenerative medicine
Categories
Funding
- National Science Foundation [EFRI1240443]
- ONR PECASE Award
- National Institutes of Health [HL092836, DE019024, EB012597, AR057837, DE021468, HL099073, EB008392]
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Graphene and its chemical derivatives have been a pivotal new class of nanomaterials and a model system for quantum behavior. The material's excellent electrical conductivity, biocompatibility, surface area and thermal properties are of much interest to the scientific community. Two-dimensional graphene materials have been widely used in various biomedical research areas such as bioelectronics, imaging, drug delivery, and tissue engineering. In this review, we will highlight the recent applications of graphene-based materials in tissue engineering and regenerative medicine. In particular, we will discuss the application of graphene-based materials in cardiac, neural, bone, cartilage, skeletal muscle, and skin/adipose tissue engineering. We will also discuss the potential risk factors of graphene-based materials in tissue engineering. In conclusion, we will outline the opportunities in the usage of graphene-based materials for clinical applications. Published by Elsevier B.V.
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