Related references
Note: Only part of the references are listed.Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation
Faxiang Li et al.
AUTOPHAGY (2018)
PHF20 collaborates with PARP1 to promote stemness and aggressiveness of neuroblastoma cells through activation of SOX2 and OCT4
Wenyong Long et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2018)
SKP2 attenuates NF-κB signaling by mediating IKKβ degradation through autophagy
Kunpeng Liu et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2018)
Identification of optineurin as an interleukin-1 receptor-associated kinase 1-binding protein and its role in regulation of MyD88-dependent signaling
Mitsuyoshi Tanishima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Amyotrophic Lateral Sclerosis
Robert H. Brown et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Optineurin in amyotrophic lateral sclerosis: Multifunctional adaptor protein at the crossroads of different neuroprotective mechanisms
Andrea Markovinovic et al.
PROGRESS IN NEUROBIOLOGY (2017)
Optineurin deficiency in mice is associated with increased sensitivity to Salmonella but does not affect proinflammatory NF-κB signaling
Karolina Slowicka et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2016)
The TBK1-binding domain of optineurin promotes type I interferon responses
Netra Pal Meena et al.
FEBS LETTERS (2016)
Decoding ALS: from genes to mechanism
J. Paul Taylor et al.
NATURE (2016)
OPTN 691_692insAG is a founder mutation causing recessive ALS and increased risk in heterozygotes
Orly Goldstein et al.
NEUROLOGY (2016)
RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS
Yasushi Ito et al.
SCIENCE (2016)
Cellular Functions of Optineurin in Health and Disease
Karolina Slowicka et al.
TRENDS IN IMMUNOLOGY (2016)
Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways
Elizabeth T. Cirulli et al.
SCIENCE (2015)
Optineurin Negatively Regulates Osteoclast Differentiation by Modulating NF-κB and Interferon Signaling: Implications for Paget's Disease
Rami Obaid et al.
CELL REPORTS (2015)
Rapid Onset of Motor Deficits in a Mouse Model of Spinocerebellar Ataxia Type 6 Precedes Late Cerebellar Degeneration1,2,3
Sriram Jayabal et al.
ENEURO (2015)
Disruption of Src Is Associated with Phenotypes Related to Williams-Beuren Syndrome and Altered Cellular Localization of TFII-I
Laleh Sinai et al.
ENEURO (2015)
Ubiquitylation of Autophagy Receptor Optineurin by HACE1 Activates Selective Autophagy for Tumor Suppression
Zhengzhao Liu et al.
CANCER CELL (2014)
The LC3 interactome at a glance
Philipp Wild et al.
JOURNAL OF CELL SCIENCE (2014)
State of play in amyotrophic lateral sclerosis genetics
Alan E. Renton et al.
NATURE NEUROSCIENCE (2014)
Abnormal Motor Phenotype at Adult Stages in Mice Lacking Type 2 Deiodinase
Soledad Barez-Lopez et al.
PLOS ONE (2014)
Effects of mutations and deletions in the human optineurin gene
Sanja Turturro et al.
SPRINGERPLUS (2014)
Optineurin and amyotrophic lateral sclerosis
Hirofumi Maruyama et al.
GERIATRICS & GERONTOLOGY INTERNATIONAL (2013)
Total alkaloids of Rubus aleaefolius Poir inhibit hepatocellular carcinoma growth in vivo and in vitro via activation of mitochondrial-dependent apoptosis
Jinyan Zhao et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2013)
Optineurin Insufficiency Impairs IRF3 but Not NF-κB Activation in Immune Cells
Ivana Munitic et al.
JOURNAL OF IMMUNOLOGY (2013)
Optineurin suppression causes neuronal cell death via NF-κB pathway
Mayumi Akizuki et al.
JOURNAL OF NEUROCHEMISTRY (2013)
Brain Inflammation and Microglia: Facts and Misconceptions
Hey-Kyeong Jeong et al.
Experimental Neurobiology (2013)
Clinico-pathological features in amyotrophic lateral sclerosis with expansions in C9ORF72
Johnathan Cooper-Knock et al.
BRAIN (2012)
A novel heterozygous nonsense mutation of the OPTN gene segregating in a Danish family with ALS
Zeynep Tumer et al.
NEUROBIOLOGY OF AGING (2012)
Novel optineurin mutations in sporadic amyotrophic lateral sclerosis patients
Marka van Blitterswijk et al.
NEUROBIOLOGY OF AGING (2012)
Polyubiquitin Binding to Optineurin Is Required for Optimal Activation of TANK-binding Kinase 1 and Production of Interferon β
Catherine E. Gleason et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Novel optineurin mutations in patients with familial and sporadic amyotrophic lateral sclerosis
R. Del Bo et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2011)
A conditional knockout resource for the genome-wide study of mouse gene function
William C. Skarnes et al.
NATURE (2011)
Analysis of OPTN as a causative gene for amyotrophic lateral sclerosis
Veronique V. Belzil et al.
NEUROBIOLOGY OF AGING (2011)
Screening of OPTN in French familial amyotrophic lateral sclerosis
Stephanie Millecamps et al.
NEUROBIOLOGY OF AGING (2011)
Optineurin Is Required for CYLD-Dependent Inhibition of TNFα-Induced NF-κB Activation
Ananthamurthy Nagabhushana et al.
PLOS ONE (2011)
Mutations of optineurin in amyotrophic lateral sclerosis
Hirofumi Maruyama et al.
NATURE (2010)
Astrogliosis in Amyotrophic Lateral Sclerosis: Role and Therapeutic Potential of Astrocytes
Marcelo R. Vargas et al.
NEUROTHERAPEUTICS (2010)
Optineurin negatively regulates TNFα-induced NF-κB activation by competing with NEMO for ubiquitinated RIP
Guozhi Zhu et al.
CURRENT BIOLOGY (2007)
Mutational analysis of the Cu/Zn superoxide dismutase gene in a Catalan ALS population:: Should all sporadic ALS cases also be screened for SOD1?
Josep Gamez et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2006)
Adult-onset primary open-angle glaucoma caused by mutations in optineurin
T Rezaie et al.
SCIENCE (2002)