Journal
ASIAN JOURNAL OF ORGANIC CHEMISTRY
Volume 7, Issue 12, Pages 2422-2426Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ajoc.201800459
Keywords
alkenes; rhodium; domino reactions; C-H activation; 2H-imidazoles
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Funding
- NSFC [21572138]
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A highly efficient Rh(III)-catalyzed one-pot reaction for the synthesis of functionalized alpha-carbonyl isoquinolines from 2H-imidazoles and alkenes has been successfully developed. This type of structure is constructed by using a transition-metal-catalyzed cascade: C-H bond activation, alkenylation, annulation, and hydrolysis.
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