Journal
ANNUAL REVIEW OF ANIMAL BIOSCIENCES, VOL 7
Volume 7, Issue -, Pages 149-172Publisher
ANNUAL REVIEWS
DOI: 10.1146/annurev-animal-020518-114955
Keywords
hermaphroditism; intersex; Amh; Mullerian duct; evolution; vertebrates
Ask authors/readers for more resources
In vertebrates, sex organs are generally specialized to perform a male or female reproductive role. Acquisition of the Mullerian duct, which gives rise to the oviduct, together with emergence of the Amh/Amhr2 system favored evolution of viviparity in jawed vertebrates. Species with high sex-specific reproductive adaptations have less potential to sex reverse, making intersex a nonfunctional condition. Teleosts, the only vertebrate group in which hermaphroditism evolved as a natural reproductive strategy, lost the Mullerian duct during evolution. They developed for gamete release complete independence from the urinary system, creating optimal anatomic and developmental preconditions for physiological sex change. The common and probably ancestral role of Amh is related to survival and proliferation of germ cells in early and adult gonads of both sexes rather than induction of Mullerian duct regression. The relationship between germ cell maintenance and sex differentiation is most evident in species in which Amh became the master male sex-determining gene.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available