4.6 Article

Catalyst-free and Solvent-free Cyanosilylation and Knoevenagel Condensation of Aldehydes

Journal

ACS SUSTAINABLE CHEMISTRY & ENGINEERING
Volume 7, Issue 1, Pages 1718-1722

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acssuschemeng.8b05486

Keywords

Catalyst-free; Solvent-free; Aldehyde; Cyanosilylation; Knoevenagel condensation

Funding

  1. National Natural Science Foundation of China [21772093]
  2. Natural Science Foundation of Jiangsu Province, China [BK20181421]
  3. Postgraduate Research & Practice Innovation Program of Jiangsu Province [KYCX17_0846]
  4. Doctorate Fellowship Foundation of Nanjing Forestry University [163360767]
  5. PAPD

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A simple catalyst-free and solvent-free method for the cyanosilylation of a variety of aldehydes with trimethylsilyl cyanide as well as the Knoevenagel condensation reaction of various aldehydes with malononitrile was developed. The developed protocol demonstrated high efficiency in the two C-C bond formation scenarios.

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