Journal
ACTA PAEDIATRICA
Volume 105, Issue 7, Pages 773-781Publisher
WILEY
DOI: 10.1111/apa.13387
Keywords
Cognitive and motor development; Early intervention; Infant Behavioral Assessment and Intervention Program; Very low birthweight; Very preterm
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Funding
- Innovatiefonds Zorgverzekeraars [576]
- Zorg Onderzoek Nederland [62200032]
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AimVarious early intervention programmes have been developed in response to the high rate of neurodevelopmental problems in very preterm infants. We investigated longitudinal effects of the Infant Behavioral Assessment and Intervention Program on cognitive and motor development of very preterm infants at the corrected ages of six months to five and a half years. MethodsThis randomised controlled trial divided 176 infants with a gestational age <32 weeks or birthweight <1500 g into intervention (n = 86) and control (n = 90) groups. Cognitive development and motor development were assessed with the Bayley Scales of Infant Development at the CAs of six, 12 and 24 months and at five and a half years with the Wechsler Preschool and Primary Scale of Intelligence and the Movement Assessment Battery for Children. ResultsWe found significant longitudinal intervention effects (0.4 SD, p = 0.006) on motor development, but no significant impact on cognitive development (p = 0.063). Infants with bronchopulmonary dysplasia showed significant longitudinal intervention effects for cognitive (0.7 SD; p = 0.019) and motor (0.9 SD; p = 0.026) outcomes. Maternal education had little effect on intervention effects over time. ConclusionThe Infant Behavioral Assessment and Intervention Program led to long-term developmental improvements in the intervention group, especially in infants with BPD.
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