Journal
OPTICAL MATERIALS EXPRESS
Volume 8, Issue 11, Pages 3277-3286Publisher
OPTICAL SOC AMER
DOI: 10.1364/OME.8.003277
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Funding
- TAMU CRI grant
- National Science Foundation [CHE-1609608]
- Office of Naval Research [N00014-16-1-2578, N00014-16-1-3054]
- Robert A. Welch Foundation [A-1547, A-1261]
- King Adulaziz City for Science and Technology (KACST)
- GURI grant
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Blood glucose monitoring is essential to avoid the unwanted consequences of glucose level fluctuations. Optical monitors are of special interest because they can be non-invasive. Among optical glucose sensors, fluorescent upconversion nanoparticles (UCNPs) have the advantage of good photostability, low toxicity, and exceptional autofluorescence suppression. However, to sense glucose, UCNPs normally need surface functionalization, and this can be easily affected by other factors in biological systems, and may also affect their ability for real-time sensing of both increasing and decreasing glucose levels. Here, we report YVO4 : Yb3+, Er3+@Nd3+ core/shell UCNPs with Nd and Yb shell and GdVO4 : Yb3+, Er3+@Nd3+ core/shell UCNPs with Nd and Yb shell that show sensitive, reversible, and selective optical glucose detection without the need for any surface functionalization or modifications. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
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