Journal
BIOMEDICAL OPTICS EXPRESS
Volume 9, Issue 12, Pages 6556-6568Publisher
OPTICAL SOC AMER
DOI: 10.1364/BOE.9.006556
Keywords
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Funding
- National Natural Science Foundation of China (NSFC) [61705088, 61525502, 61435006, 61775085, 61601199, 61575082, 61490715]
- Local Innovation and Research Teams Project of Guangdong Pearl River Talents Program [2017BT01X121]
- Youth Science and Technology Innovation Talents of Guangdong [2015TQ01X606]
- Pearl River S&T Nova Program of Guangzhou [201710010051]
- Science and Technology Planning Project of Guangdong Province [2017B010123005]
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Optical polarization imaging has played an important role in many biological and biomedical applications, as it provides a label-free and non-invasive detection scheme to reveal the polarization information of optical rotation, birefringence, and photoelasticity distribution inherent in biological samples. However, the imaging speeds of the previously demonstrated polarization imaging techniques were often limited by the slow frame rates of the arrayed imaging detectors, which usually run at frame rates of several hundred hertz. By combining the optical coherent detection of orthogonal polarizations and the optical time-stretch imaging technique, we achieved ultrafast polarization bio-imaging at an extremely fast record line scanning rate up to 100 MHz without averaging. We experimentally demonstrated the superior performance of our method by imaging three slices of different kinds of biological samples with the retrieved Jones matrix and polarization-sensitive information including birefringence and diattenuation. The proposed system in this paper may find potential applications for ultrafast polarization dynamics in living samples or some other advanced biomedical research. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
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