Journal
JOURNAL OF GERIATRIC ONCOLOGY
Volume 10, Issue 4, Pages 528-533Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jgo.2018.09.008
Keywords
Older patients with lung cancer; Treatment; Chemotherapy; Immunotherapy; Targeted therapy; Geriatric assessment
Categories
Ask authors/readers for more resources
With a median age of 70 years at diagnosis, lung cancer is a disease of older persons. As a consequence oncologists are confronted with an increasing older lung cancer population for which treatment decisions are needed. In the past years, the therapeutic landscape of advanced non-small cell lung cancer (NSCLC) has changed impressively with the introduction of targeted therapies and immunotherapy next to chemotherapy. Treatment choices for advanced NSCLC are mainly guided by different tumor-related characteristics. However, in older patients treatment decisions are more complex because of the scarcity of data from large randomized studies in older patients and the heterogeneity of this population with regards to different geriatric domains such as functional status, co-morbidity and polypharmacy. The present manuscript reviews available data for the different treatment options for older patients with NSCLC as well as the use of geriatric assessment as an evaluation and guidance tool. (C) 2018 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available