Journal
VOX SANGUINIS
Volume 114, Issue 1, Pages 95-102Publisher
WILEY
DOI: 10.1111/vox.12717
Keywords
blood groups; genetics; terminology
Categories
Funding
- Australian Red Cross Blood Service
- Australian Governments
- Intramural Research Program of the NIH Clinical Center [Z99 CL999999]
- Laboratoire d'Excellence GR-Ex
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Background and objectives The International Society of Blood Transfusion (ISBT) Working Party for Red Cell Immunogenetics and Blood Group Terminology meets in association with the ISBT congress and has met three times since the last report: at the international meetings held in Dubai, United Arab Emirates, September 2016 and Toronto, Canada, June 2018; and at a regional congress in Copenhagen, Denmark, June 2017 for an interim session. Methods As in previous meetings, matters pertaining to blood group antigen nomenclature and classification were discussed. New blood group antigens were approved and named according to the serologic and molecular evidence presented. Results and conclusions Fifteen new blood group antigens were added to eight blood group systems. One antigen was made obsolete based on additional data. Consequently, the current total of blood group antigens recognized by the ISBT is 360, of which 322 are clustered within 36 blood groups systems. The remaining 38 antigens are currently unassigned to a known system. Clinically significant blood group antigens continue to be discovered, through serology/sequencing and/or recombinant or genomic technologies.
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