Related references
Note: Only part of the references are listed.P2X purinoceptors as a link between hyperexcitability and neuroinflammation in status epilepticus
David C. Henshall et al.
EPILEPSY & BEHAVIOR (2015)
Autism spectrum disorder and epilepsy: Disorders with a shared biology
Bo Hoon Lee et al.
EPILEPSY & BEHAVIOR (2015)
Identifying the biological pathways underlying human focal epilepsy: from complexity to coherence to centrality
Nasir Mirza et al.
HUMAN MOLECULAR GENETICS (2015)
Role of fractalkine-CX3CR1 pathway in seizure-induced microglial activation, neurodegeneration, and neuroblast production in the adult rat brain
Idrish Ali et al.
NEUROBIOLOGY OF DISEASE (2015)
A Peptide Uncoupling BDNF Receptor TrkB from Phospholipase Cγ1 Prevents Epilepsy Induced by Status Epilepticus
Bin Gu et al.
NEURON (2015)
Prospects of epileptogenesis prevention
Iwona Radzik et al.
PHARMACOLOGICAL REPORTS (2015)
Role of mTOR inhibitors in epilepsy treatment
Krzysztof Sadowski et al.
PHARMACOLOGICAL REPORTS (2015)
Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus
Michael R. Johnson et al.
NATURE COMMUNICATIONS (2015)
Abnormal Microglial Activation in the Cstb-/- Mouse, A Model for Progressive Myoclonus Epilepsy, EPM1
Olesya Okuneva et al.
GLIA (2015)
Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2
Deepti Chugh et al.
PLOS ONE (2015)
Early molecular and behavioral response to lipopolysaccharide in the WAG/Rij rat model of absence epilepsy and depressive-like behavior, involves interplay between AMPK, AKT/mTOR pathways and neuroinflammatory cytokine release
Emilio Russo et al.
BRAIN BEHAVIOR AND IMMUNITY (2014)
P2X7 Receptor Inhibition Interrupts the Progression of Seizures in Immature Rats and Reduces Hippocampal Damage
Guillaume Mesuret et al.
CNS NEUROSCIENCE & THERAPEUTICS (2014)
Epilepsy in newborns with tuberous sclerosis complex
Katarzyna Kotulska et al.
EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY (2014)
Should losartan be administered following brain injury?
Alon Friedman et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2014)
N-Cadherin Regulates Molecular Organization of Excitatory and Inhibitory Synaptic Circuits in Adult Hippocampus In Vivo
Jessica S. Nikitczuk et al.
HIPPOCAMPUS (2014)
mTOR Signaling Inhibition Modulates Macrophage/Microglia-Mediated Neuroinflammation and Secondary Injury via Regulatory T Cells after Focal Ischemia
Luokun Xie et al.
JOURNAL OF IMMUNOLOGY (2014)
De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyriapolydactyly-hydrocephalus syndrome
Ghayda M. Mirzaa et al.
NATURE GENETICS (2014)
The mTOR signaling pathway and neuronal stem/progenitor cell proliferation in the hippocampus are altered during the development of absence epilepsy in a genetic animal model
Emilio Russo et al.
NEUROLOGICAL SCIENCES (2014)
Concentration of Il-1β, Il-2, Il-6, TNFα in the blood serum in children with generalized epilepsy treated by valproate
Barbara Steinborn et al.
PHARMACOLOGICAL REPORTS (2014)
Evidence for mTOR pathway activation in a spectrum of epilepsy-associated pathologies
Joan Liu et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2014)
Everolimus Treatment of Refractory Epilepsy in Tuberous Sclerosis Complex
Darcy A. Krueger et al.
ANNALS OF NEUROLOGY (2013)
High-dose rapamycin blocks mossy fiber sprouting but not seizures in a mouse model of temporal lobe epilepsy
Kathleen Heng et al.
EPILEPSIA (2013)
Fractalkine/CX3CLI modulates GABAA currents in human temporal lobe epilepsy
Cristina Roseti et al.
EPILEPSIA (2013)
Autoantibodies to neuronal antigens in children with new-onset seizures classified according to the revised ILAE organization of seizures and epilepsies
Jehan Suleiman et al.
EPILEPSIA (2013)
Immunology of stiff person syndrome and other GAD-associated neurological disorders
Harry Alexopoulos et al.
EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2013)
A critical review of mTOR inhibitors and epilepsy: from basic science to clinical trials
Michael Wong
EXPERT REVIEW OF NEUROTHERAPEUTICS (2013)
Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis
Rebecca L. Williams-Karnesky et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Intracellular and circulating neuronal antinuclear antibodies in human epilepsy
Philip H. Iffland et al.
NEUROBIOLOGY OF DISEASE (2013)
mTOR inhibition modulates epileptogenesis, seizures and depressive behavior in a genetic rat model of absence epilepsy
Emilio Russo et al.
NEUROPHARMACOLOGY (2013)
Rapamycin Reverses Status Epilepticus-Induced Memory Deficits and Dendritic Damage
Amy L. Brewster et al.
PLOS ONE (2013)
Vigabatrin Inhibits Seizures and mTOR Pathway Activation in a Mouse Model of Tuberous Sclerosis Complex
Bo Zhang et al.
PLOS ONE (2013)
Spatiotemporal Characterization of mTOR Kinase Activity Following Kainic Acid Induced Status Epilepticus and Analysis of Rat Brain Response to Chronic Rapamycin Treatment
Matylda Macias et al.
PLOS ONE (2013)
Altered Expression of CX3CL1 in Patients with Epilepsy and in a Rat Model
Yali Xu et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Epileptic Encephalitis: The Role of the Innate and Adaptive Immune System
Jan Bauer et al.
BRAIN PATHOLOGY (2012)
mTOR inhibitors in cancer therapy
Yekaterina Y. Zaytseva et al.
CANCER LETTERS (2012)
Blood-brain barrier dysfunction and epilepsy: Pathophysiologic role and therapeutic approaches
Nicola Marchi et al.
EPILEPSIA (2012)
Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood-brain barrier leakage but not microglia activation
Erwin A. van Vliet et al.
EPILEPSIA (2012)
Effective everolimus treatment of inoperable, life-threatening subependymal giant cell astrocytoma and intractable epilepsy in a patient with tuberous sclerosis complex
Marta Perek-Polnik et al.
EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY (2012)
Management of epilepsy associated with tuberous sclerosis complex (TSC): Clinical recommendations
Paolo Curatolo et al.
EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY (2012)
IgG Leakage May Contribute to Neuronal Dysfunction in Drug-Refractory Epilepsies With Blood-Brain Barrier Disruption
Zuzanna Michalak et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2012)
Interleukin-1 Receptor Accessory Protein Organizes Neuronal Synaptogenesis as a Cell Adhesion Molecule
Tomoyuki Yoshida et al.
JOURNAL OF NEUROSCIENCE (2012)
Post-treatment with rapamycin does not prevent epileptogenesis in the amygdala stimulation model of temporal lobe epilepsy
Anna Sliwa et al.
NEUROSCIENCE LETTERS (2012)
Altered Synaptic Properties During Integration of Adult-Born Hippocampal Neurons Following a Seizure Insult
Johanna Jackson et al.
PLOS ONE (2012)
The Interaction between Early Life Epilepsy and Autistic-Like Behavioral Consequences: A Role for the Mammalian Target of Rapamycin (mTOR) Pathway
Delia M. Talos et al.
PLOS ONE (2012)
Immune modulation of learning, memory, neural plasticity and neurogenesis
Raz Yirmiya et al.
BRAIN BEHAVIOR AND IMMUNITY (2011)
Inhibition of the mammalian target of rapamycin blocks epilepsy progression in NS-Pten conditional knockout mice
C. Nicole Sunnen et al.
EPILEPSIA (2011)
Therapeutic value of prenatal rapamycin treatment in a mouse brain model of tuberous sclerosis complex
Stefanie Anderl et al.
HUMAN MOLECULAR GENETICS (2011)
Stiff-person syndrome (SPS) and anti-GAD-related CNS degenerations: Protean additions to the autoimmune central neuropathies
Fatima Ali et al.
JOURNAL OF AUTOIMMUNITY (2011)
Rapamycin Suppresses Mossy Fiber Sprouting But Not Seizure Frequency in a Mouse Model of Temporal Lobe Epilepsy
Paul S. Buckmaster et al.
JOURNAL OF NEUROSCIENCE (2011)
The role of inflammation in epilepsy
Annamaria Vezzani et al.
NATURE REVIEWS NEUROLOGY (2011)
Astrocytes: biology and pathology
Michael V. Sofroniew et al.
ACTA NEUROPATHOLOGICA (2010)
Interneurons, GABA currents, and subunit composition of the GABA(A) receptor in type I and type II cortical dysplasia
Veronique M. Andre et al.
EPILEPSIA (2010)
Hippocampal FGF-2 and BDNF overexpression attenuates epileptogenesis-associated neuroinflammation and reduces spontaneous recurrent seizures
Roberta Bovolenta et al.
JOURNAL OF NEUROINFLAMMATION (2010)
VASCULAR CHANGES IN EPILEPSY: FUNCTIONAL CONSEQUENCES AND ASSOCIATION WITH NETWORK PLASTICITY IN PILOCARPINE-INDUCED EXPERIMENTAL EPILEPSY
X. E. Ndode-Ekane et al.
NEUROSCIENCE (2010)
Everolimus for Subependymal Giant-Cell Astrocytomas in Tuberous Sclerosis.
Darcy A. Krueger et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Neuroprotection and epileptogenesis
Stanislaw J. Czuczwar
PHARMACOLOGICAL REPORTS (2010)
Association of Intronic Polymorphism rs3773364 A>G in Synapsin-2 Gene With Idiopathic Epilepsy
Ram Lakhan et al.
SYNAPSE (2010)
Enhanced microglial activation and proinflammatory cytokine upregulation are linked to increased susceptibility to seizures and neurologic injury in a 'two-hit' seizure model
Kathleen C. Somera-Molina et al.
BRAIN RESEARCH (2009)
Rapamycin Reduces Seizure Frequency in Tuberous Sclerosis Complex
Jennifer Muncy et al.
JOURNAL OF CHILD NEUROLOGY (2009)
Tumor necrosis factor receptor-associated protein 1 regulates cell adhesion and synaptic morphology via modulation of N-cadherin expression
Kyoko Kubota et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Inhibition of the Mammalian Target of Rapamycin Signaling Pathway Suppresses Dentate Granule Cell Axon Sprouting in a Rodent Model of Temporal Lobe Epilepsy
Paul S. Buckmaster et al.
JOURNAL OF NEUROSCIENCE (2009)
The Mammalian Target of Rapamycin Signaling Pathway Mediates Epileptogenesis in a Model of Temporal Lobe Epilepsy
Ling-Hui Zeng et al.
JOURNAL OF NEUROSCIENCE (2009)
CCR3, CCR2A and macrophage inflammatory protein (MIP)-1α, monocyte chemotactic protein-1 (MCP-1) in the mouse hippocampus during and after pilocarpine-induced status epilepticus (PISE)
J. H. Xu et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2009)
Localized delivery of fibroblast growth factor-2 and brain-derived neurotrophic factor reduces spontaneous seizures in an epilepsy model
Beatrice Paradiso et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Role of microglia in neuronal degeneration and regeneration
Lisa Walter et al.
SEMINARS IN IMMUNOPATHOLOGY (2009)
Molecular dissection of reactive astrogliosis and glial scar formation
Michael V. Sofroniew
TRENDS IN NEUROSCIENCES (2009)
Immunoregulatory functions of mTOR inhibition
Angus W. Thomson et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex
Ling-Hui Zeng et al.
ANNALS OF NEUROLOGY (2008)
Spectrum of neurological syndromes associated with glutamic acid decarboxylase antibodies: diagnostic clues for this association
Albert Saiz et al.
BRAIN (2008)
The role of cytokines in the pathophysiology of epilepsy
Annamaria Vezzani et al.
BRAIN BEHAVIOR AND IMMUNITY (2008)
Valproic acid attenuates inflammation in experimental autoimmune neuritis
Z. Zhang et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Glia as a source of cytokines: Implications for neuronal excitability and survival
Annamaria Vezzani et al.
EPILEPSIA (2008)
Do cytokines have any role in epilepsy?
S. Sinha et al.
EPILEPSY RESEARCH (2008)
Blockade of microglial glutamate release protects against ischemic brain injury
Hideyuki Takeuchi et al.
EXPERIMENTAL NEUROLOGY (2008)
Cytokine mechanisms of central sensitization:: Distinct and overlapping role of interleukin-1β, interleukin-6, and tumor necrosis factor-β in regulating synaptic and neuronal activity in the superficial spinal cord
Yasuhiko Kawasaki et al.
JOURNAL OF NEUROSCIENCE (2008)
Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: Effects on mTORC1 and Akt signaling lead to improved survival and function
Lynsey Meikle et al.
JOURNAL OF NEUROSCIENCE (2008)
Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury
Silvia Carloni et al.
NEUROBIOLOGY OF DISEASE (2008)
The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease
Ben A. Barres
NEURON (2008)
Progress in neuroprotective strategies for preventing epilepsy
Munjal M. Acharya et al.
PROGRESS IN NEUROBIOLOGY (2008)
The adenosine kinase hypothesis of epileptogenesis
Deflev Boison
PROGRESS IN NEUROBIOLOGY (2008)
Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study
Gianpiero L. Cavalleri et al.
LANCET NEUROLOGY (2007)
Complement activation in experimental and human temporal lobe epilepsy
E. Aronica et al.
NEUROBIOLOGY OF DISEASE (2007)
Seizure-promoting effect of blood-brain barrier disruption
Nicola Marchi et al.
EPILEPSIA (2007)
Blood-brain barrier leakage may lead to progression of temporal lobe epilepsy
E. A. van Vliet et al.
BRAIN (2007)
TGF-β receptor-mediated albumin uptake into astrocytes is involved in neocortical epileptogenesis
Sebastian Ivens et al.
BRAIN (2007)
What is the blood-brain barrier (not)?
Ingo Bechmann et al.
TRENDS IN IMMUNOLOGY (2007)
Brain CD8+ and cytotoxic T lymphocytes are associated with, and may be specific for, human immunodeficiency virus type 1 encephalitis in patients with acquired immunodeficiency syndrome
Carol K. Petito et al.
JOURNAL OF NEUROVIROLOGY (2006)
Cyclooxygenase-2 inhibitor, celecoxib, inhibits the altered hippocampal neurogenesis with attenuation of spontaneous recurrent seizures following pilocarpine-induced status epilepticus
Keun-Hwa Jung et al.
NEUROBIOLOGY OF DISEASE (2006)
Tumor necrosis factor-α induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner
Hideyuki Takeuchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Minocycline inhibits caspase-dependent and -independent cell death pathways and is neuroprotective against hippocampal damage after treatment with kainic acid in mice
Kyoung Heo et al.
NEUROSCIENCE LETTERS (2006)
Astrocyte dysfunction in neurological disorders:: a molecular perspective
G Seifert et al.
NATURE REVIEWS NEUROSCIENCE (2006)
Mouse spinal cord compression injury is reduced by either activation of the adenosine A(2A) receptor on bone marrow-derived cells or deletion of the A(2A) receptor on non-bone marrow-derived cells
Y. Li et al.
NEUROSCIENCE (2006)
Control of dendritic arborization by the phosphoinositide-3'-kinase-Akt-mammalian target of rapamycin pathway
J Jaworski et al.
JOURNAL OF NEUROSCIENCE (2005)
Brain inflammation in epilepsy: Experimental and clinical evidence
A Vezzani et al.
EPILEPSIA (2005)
Interleukin-1 and neuronal injury
SM Allan et al.
NATURE REVIEWS IMMUNOLOGY (2005)
Identification of a mutation in synapsin I, a synaptic vesicle protein, in a family with epilepsy
CC Garcia et al.
JOURNAL OF MEDICAL GENETICS (2004)
Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex
E Seiffert et al.
JOURNAL OF NEUROSCIENCE (2004)
Megalencephaly and perisylvian polymicrogyria with postaxial polydactyly and hydrocephalus: A rare brain malformation syndrome associated with mental retardation and seizures
G Mirzaa et al.
NEUROPEDIATRICS (2004)
Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload
JR McMullen et al.
CIRCULATION (2004)
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
B Ravikumar et al.
NATURE GENETICS (2004)
Inflammation is detrimental for neurogenesis in adult brain
CT Ekdahl et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
L Santarelli et al.
SCIENCE (2003)
Macrophages and microglia in central nervous system injury: Are they helpful or harmful?
M Schwartz
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2003)
Melatonin attenuates kainic acid-induced hippocampal neurodegeneration and oxidative stress through microglial inhibition
SY Chung et al.
JOURNAL OF PINEAL RESEARCH (2003)
Tuberous sclerosis: from tubers to mTOR
DJ Kwiatkowski
ANNALS OF HUMAN GENETICS (2003)
A new neuromodulatory pathway with a glial contribution mediated via A2a adenosine receptors
T Nishizaki et al.
GLIA (2002)
Immunohistochemical analysis of anti-Hu-associated paraneoplastic encephalomyelitis
F Bernal et al.
ACTA NEUROPATHOLOGICA (2002)
Diagnosis and staging of Rasmussen's encephalitis by serial MRI and histopathology
CG Bien et al.
NEUROLOGY (2002)
Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin
TA Huffman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Destruction of neurons by cytotoxic T cells: A new pathogenic mechanism in Rasmussen's encephalitis
CG Bien et al.
ANNALS OF NEUROLOGY (2002)
Microglia in neurodegeneration: Molecular aspects
PJ Gebicke-Haerter
MICROSCOPY RESEARCH AND TECHNIQUE (2001)
Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: Meta-analysis of controlled trials
NR Temkin
EPILEPSIA (2001)
Neurogenesis in the adult is involved in the formation of trace memories
TJ Shors et al.
NATURE (2001)
Novel, non-antigen-specific therapeutic approaches to autoimmune/inflammatory diseases
GG Illei et al.
CURRENT OPINION IN IMMUNOLOGY (2000)
Alterations in bcl-2 and caspase gene family protein expression in human temporal lobe epilepsy
DC Henshall et al.
NEUROLOGY (2000)
Sodium valproate inhibits production of TNF-α and IL-6 and activation of NF-κB
T Ichiyama et al.
BRAIN RESEARCH (2000)