4.6 Article

Soluble pre-fibrillar tau and β-amyloid species emerge in early human Alzheimer's disease and track disease progression and cognitive decline

Related references

Note: Only part of the references are listed.
Article Clinical Neurology

Characterization of Early Pathological Tau Conformations and Phosphorylation in Chronic Traumatic Encephalopathy

Nicholas M. Kanaan et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2016)

Article Clinical Neurology

Thal Amyloid Stages Do Not Significantly Impact the Correlation Between Neuropathological Change and Cognition in the Alzheimer Disease Continuum

Alberto Serrano-Pozo et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2016)

Article Geriatrics & Gerontology

Braak staging, plaque pathology, and APOE status in elderly persons without cognitive impairment

Elliott J. Mufson et al.

NEUROBIOLOGY OF AGING (2016)

Article Cell Biology

Tau and Aβ imaging, CSF measures, and cognition in Alzheimer's disease

Matthew R. Brier et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Article Multidisciplinary Sciences

Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory

M. Fa et al.

SCIENTIFIC REPORTS (2016)

Article Biochemistry & Molecular Biology

Kinetic regime of dithiothreitol-induced aggregation of bovine serum albumin

Vera A. Borzova et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2015)

Article Multidisciplinary Sciences

SDS-PAGE analysis of Aβ oligomers is disserving research into Alzheimer's disease: appealing for ESI-IM-MS

Rosa Pujol-Pina et al.

SCIENTIFIC REPORTS (2015)

Article Clinical Neurology

A comparison of Aβ amyloid pathology staging systems and correlation with clinical diagnosis

Susana Boluda et al.

ACTA NEUROPATHOLOGICA (2014)

Article Neurosciences

Knock-In of Human BACE1 Cleaves Murine APP and Reiterates Alzheimer-like Phenotypes

Kaja Plucinska et al.

JOURNAL OF NEUROSCIENCE (2014)

Article Clinical Neurology

Memory deficits correlate with tau and spine pathology in P301S MAPT transgenic mice

H. Xu et al.

NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2014)

Article Clinical Neurology

Amyloid-β and Tau The Trigger and Bullet in Alzheimer Disease Pathogenesis

George S. Bloom

JAMA NEUROLOGY (2014)

Article Neurosciences

Soluble amyloid beta levels are elevated in the white matter of Alzheimer's patients, independent of cortical plaque severity

Lyndsey E. Collins-Praino et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2014)

Article Clinical Neurology

Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples

Andrew D. Watt et al.

ACTA NEUROPATHOLOGICA (2013)

Article Clinical Neurology

Brain amyloid-β oligomers in ageing and Alzheimer's disease

Sylvain E. Lesne et al.

BRAIN (2013)

Review Clinical Neurology

Hyperphosphorylation-induced tau of gomers

Khalid Iqbal et al.

FRONTIERS IN NEUROLOGY (2013)

Article Neurosciences

Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody

Katherine L. Youmans et al.

MOLECULAR NEURODEGENERATION (2012)

Article Multidisciplinary Sciences

Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β

Justin M. Nussbaum et al.

NATURE (2012)

Article Biochemistry & Molecular Biology

Characterization of Prefibrillar Tau Oligomers in Vitro and in Alzheimer Disease

Kristina R. Patterson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Neurosciences

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

Cristian A. Lasagna-Reeves et al.

MOLECULAR NEURODEGENERATION (2011)

Article Biochemistry & Molecular Biology

Preparation and Characterization of Neurotoxic Tau Oligomers

Cristian A. Lasagna-Reeves et al.

BIOCHEMISTRY (2010)

Article Biochemistry & Molecular Biology

BACE1 and BACE2 enzymatic activities in Alzheimer's disease

Rachel R. Ahmed et al.

JOURNAL OF NEUROCHEMISTRY (2010)

Article Biochemistry & Molecular Biology

How do surfactants and DTT affect the size, dynamics, activity and growth of soluble lysozyme aggregates?

Satish Kumar et al.

BIOCHEMICAL JOURNAL (2008)

Article Biochemistry & Molecular Biology

Heat-induced conversion of β2-Microglobulin and hen egg-white lysozyme into amyloid fibrils

Kenji Sasahara et al.

JOURNAL OF MOLECULAR BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Accelerating amyloid-β fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models

Irene H. Cheng et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Neurosciences

Accumulation of pathological tau species and memory loss in a conditional model of tauopathy

Zdenek Berger et al.

JOURNAL OF NEUROSCIENCE (2007)

Article Geriatrics & Gerontology

Tau protein abnormalities associated with the progression of alzheimer disease type dementia

V. Haroutunian et al.

NEUROBIOLOGY OF AGING (2007)

Article Biochemistry & Molecular Biology

Solution state characterization of amyloid β-derived diffusible ligands

Robert W. Hepler et al.

BIOCHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Altered β-secretase enzyme kinetics and levels of both BACE1 and BACE2 in the Alzheimer's disease brain

John H. Stockley et al.

FEBS LETTERS (2006)

Article Biochemistry & Molecular Biology

Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage:: in vitro evidence and implications for tangle formation in vivo

AL Guillozet-Bongaarts et al.

JOURNAL OF NEUROCHEMISTRY (2006)

Article Multidisciplinary Sciences

A specific amyloid-β protein assembly in the brain impairs memory

S Lesné et al.

NATURE (2006)

Article Clinical Neurology

Neuropathologic substrate of mild cognitive impairment

WR Markesbery et al.

ARCHIVES OF NEUROLOGY (2006)

Article Biochemistry & Molecular Biology

Globular amyloid β-peptide1-42 oligomer -: a homogenous and stable neuropathological protein in Alzheimer's disease

S Barghorn et al.

JOURNAL OF NEUROCHEMISTRY (2005)

Article Multidisciplinary Sciences

Tau suppression in a neurodegenerative mouse model improves memory function

K SantaCruz et al.

SCIENCE (2005)

Article Biochemistry & Molecular Biology

Neurotoxic protein oligomers - what you see is not always what you get

G Bitan et al.

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS (2005)

Article Clinical Neurology

β-secretase protein and activity are increased in the neocortex in Alzheimer disease

H Fukumoto et al.

ARCHIVES OF NEUROLOGY (2002)

Article Clinical Neurology

Increased expression of the amyloid precursor β-secretase in Alzheimer's disease

RMD Holsinger et al.

ANNALS OF NEUROLOGY (2002)

Review Neurosciences

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders

L Buée et al.

BRAIN RESEARCH REVIEWS (2000)

Article Clinical Neurology

Sequence of Aβ-protein deposition in the human medial temporal lobe

DR Thal et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2000)

Article Medicine, General & Internal

Correlation between elevated levels of amyloid β-peptide in the brain and cognitive decline

J Näslund et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2000)

Article Biochemistry & Molecular Biology

Differential assembly of human tau isoforms in the presence of arachidonic acid

ME King et al.

JOURNAL OF NEUROCHEMISTRY (2000)

Article Geriatrics & Gerontology

Conformational change as one of the earliest alterations of tan in Alzheimer's disease

CL Weaver et al.

NEUROBIOLOGY OF AGING (2000)